Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3708062..3708703 Replicon chromosome
Accession NZ_CP061592
Organism Acinetobacter seifertii strain AS60

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC789_RS17725 Protein ID WP_077168983.1
Coordinates 3708062..3708451 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC789_RS17730 Protein ID WP_151276929.1
Coordinates 3708458..3708703 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC789_RS17710 3703174..3705369 - 2196 WP_019457776.1 TRAP transporter large permease subunit -
IC789_RS17715 3705557..3706123 - 567 WP_004705397.1 rhombosortase -
IC789_RS17720 3706208..3707293 - 1086 WP_019457778.1 hypothetical protein -
IC789_RS17725 3708062..3708451 - 390 WP_077168983.1 hypothetical protein Toxin
IC789_RS17730 3708458..3708703 - 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC789_RS17735 3708905..3710077 + 1173 WP_077168982.1 acyl-CoA dehydrogenase family protein -
IC789_RS17740 3710127..3711617 - 1491 WP_077168981.1 NAD(P)/FAD-dependent oxidoreductase -
IC789_RS17745 3711799..3712176 - 378 WP_002049717.1 50S ribosomal protein L17 -
IC789_RS17750 3712195..3713202 - 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15626.79 Da        Isoelectric Point: 9.8344

>T172748 WP_077168983.1 NZ_CP061592:c3708451-3708062 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Download         Length: 390 bp

>T172748 NZ_CP079903:c1297385-1297107 [Pseudomonas juntendi]
ATGATTCAAAGCTTCAGCTGTGCCGACACGGAAGCACTATTTGTTACTGGAAAAACGCGACGTTGGTCAGATATCAAATC
AGTCGCGGAGCGCAAACTGGCCATGCTCGATGCCGCAACAGAGCTGCGAGACCTGCGATCGCCACCTGGCAACCGCCTCG
AGGCGTTGAGCGGCAACCGTGCCGGTCAGCACAGCATTCGCGTCAATGACCAATGGCGCTTGTGCTTCACCTGGACCGAC
AACGGGCCGGCCAACGTTGAAATTATCGATTACCACTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT172748 WP_151276929.1 NZ_CP061592:c3708703-3708458 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT172748 NZ_CP079903:c1297098-1296799 [Pseudomonas juntendi]
ATGCTCAAGAACGGTATGCGTCCAATCCATCCCGGTGAAGTCCTGCGTGAGGACTTCCAGAAAGAAATGGGCTTCAGTGC
TGCGGCATTGGCCAGGGCGCTGGGCGTCGCCACTCCAACCGTCAACAATATCCTGCGCGAACGGGGCGGTGTTTCCGCCG
ATATGGCGCTGCGTCTGTCCATTTGCCTGGATACTACCCCCGAGTTCTGGCTCAACCTGCAGACCGCCTTCGATCTGCGC
ACCGCCGAACAGCGACACGGTGAAGAGATCATCGGGGCGGTACAGCGCCTGGTCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References