Detailed information of TA system TA172748

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3708062..3708703
• Replicon: chromosome
• Accession: NZ_CP061592
• Organism: Acinetobacter seifertii strain AS60

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: IC789_RS17725
• Protein ID: WP_077168983.1
• Coordinates: 3708062..3708451 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: IC789_RS17730
• Protein ID: WP_151276929.1
• Coordinates: 3708458..3708703 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IC789_RS17710	3703174..3705369	-	2196	WP_019457776.1	TRAP transporter large permease subunit	-
IC789_RS17715	3705557..3706123	-	567	WP_004705397.1	rhombosortase	-
IC789_RS17720	3706208..3707293	-	1086	WP_019457778.1	hypothetical protein	-
IC789_RS17725	3708062..3708451	-	390	WP_077168983.1	hypothetical protein	Toxin
IC789_RS17730	3708458..3708703	-	246	WP_151276929.1	succinate dehydrogenase assembly factor 2	Antitoxin
IC789_RS17735	3708905..3710077	+	1173	WP_077168982.1	acyl-CoA dehydrogenase family protein	-
IC789_RS17740	3710127..3711617	-	1491	WP_077168981.1	NAD(P)/FAD-dependent oxidoreductase	-
IC789_RS17745	3711799..3712176	-	378	WP_002049717.1	50S ribosomal protein L17	-
IC789_RS17750	3712195..3713202	-	1008	WP_004705386.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15626.79 Da
• Isoelectric Point: 9.8344

>T172748 WP_077168983.1 NZ_CP061592:c3708451-3708062 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Nucleotide

• Length: 390 bp

>T172748 NZ_CP079903:c1297385-1297107 [Pseudomonas juntendi]
ATGATTCAAAGCTTCAGCTGTGCCGACACGGAAGCACTATTTGTTACTGGAAAAACGCGACGTTGGTCAGATATCAAATC
AGTCGCGGAGCGCAAACTGGCCATGCTCGATGCCGCAACAGAGCTGCGAGACCTGCGATCGCCACCTGGCAACCGCCTCG
AGGCGTTGAGCGGCAACCGTGCCGGTCAGCACAGCATTCGCGTCAATGACCAATGGCGCTTGTGCTTCACCTGGACCGAC
AACGGGCCGGCCAACGTTGAAATTATCGATTACCACTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9802.20 Da
• Isoelectric Point: 5.1802

>AT172748 WP_151276929.1 NZ_CP061592:c3708703-3708458 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT172748 NZ_CP079903:c1297098-1296799 [Pseudomonas juntendi]
ATGCTCAAGAACGGTATGCGTCCAATCCATCCCGGTGAAGTCCTGCGTGAGGACTTCCAGAAAGAAATGGGCTTCAGTGC
TGCGGCATTGGCCAGGGCGCTGGGCGTCGCCACTCCAACCGTCAACAATATCCTGCGCGAACGGGGCGGTGTTTCCGCCG
ATATGGCGCTGCGTCTGTCCATTTGCCTGGATACTACCCCCGAGTTCTGGCTCAACCTGCAGACCGCCTTCGATCTGCGC
ACCGCCGAACAGCGACACGGTGAAGAGATCATCGGGGCGGTACAGCGCCTGGTCGCCTGA