Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3672965..3673606 Replicon chromosome
Accession NZ_CP061578
Organism Acinetobacter seifertii strain AS63

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC792_RS17500 Protein ID WP_077168983.1
Coordinates 3672965..3673354 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC792_RS17505 Protein ID WP_151276929.1
Coordinates 3673361..3673606 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC792_RS17485 3668076..3670271 - 2196 WP_019457776.1 TRAP transporter large permease subunit -
IC792_RS17490 3670459..3671025 - 567 WP_004705397.1 rhombosortase -
IC792_RS17495 3671110..3672195 - 1086 WP_019457778.1 hypothetical protein -
IC792_RS17500 3672965..3673354 - 390 WP_077168983.1 hypothetical protein Toxin
IC792_RS17505 3673361..3673606 - 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC792_RS17510 3673808..3674980 + 1173 WP_077168982.1 acyl-CoA dehydrogenase family protein -
IC792_RS17515 3675030..3676520 - 1491 WP_077168981.1 NAD(P)/FAD-dependent oxidoreductase -
IC792_RS17520 3676702..3677079 - 378 WP_002049717.1 50S ribosomal protein L17 -
IC792_RS17525 3677098..3678105 - 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15626.79 Da        Isoelectric Point: 9.8344

>T172743 WP_077168983.1 NZ_CP061578:c3673354-3672965 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Download         Length: 390 bp

>T172743 NZ_CP079891:4531572-4531970 [Escherichia fergusonii]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCCGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATTTATGGGGCAGAAAAAAGCCAGATGCCAG
AACGCAATTTGGCGGTGATTGAAGGCTTCGTATCTCGTTTGGAAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACT
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCCGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCTGGAATCAGACTAGAAGACTGGAGCTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT172743 WP_151276929.1 NZ_CP061578:c3673606-3673361 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT172743 NZ_CP079891:4531345-4531572 [Escherichia fergusonii]
ATGGAAACCACTGTATTTTTAAGTAATCGCAGTCAGGCTGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGACGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References