Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2445485..2445756 Replicon chromosome
Accession NZ_CP061530
Organism Escherichia coli strain WEM25

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2445523..2445626 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2445485..2445756 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5V41_RS11900 2442642..2444081 + 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H5V41_RS11905 2444199..2444435 + 237 WP_001338166.1 DUF1480 family protein -
H5V41_RS11910 2444540..2444731 + 192 WP_001338167.1 YebW family protein -
H5V41_RS11915 2444732..2445388 - 657 WP_000812732.1 protein-serine/threonine phosphatase -
- 2445485..2445756 + 272 - - Antitoxin
- 2445523..2445626 - 104 - - Toxin
H5V41_RS11920 2445784..2446125 - 342 WP_000976472.1 YebY family protein -
H5V41_RS11925 2446138..2447010 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
H5V41_RS11930 2447014..2447388 - 375 WP_000168747.1 CopC domain-containing protein YobA -
H5V41_RS11935 2447527..2447757 + 231 WP_000916763.1 DNA polymerase III subunit theta -
H5V41_RS11940 2447859..2448515 + 657 WP_190811846.1 carbon-nitrogen hydrolase family protein -
H5V41_RS11945 2448539..2449201 + 663 WP_000944258.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T172718 NZ_CP061530:c2445626-2445523 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT172718 NZ_CP061530:2445485-2445756 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATAGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References