Detailed information of TA system TA172687

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 473616..474257
• Replicon: chromosome
• Accession: NZ_CP061525
• Organism: Acinetobacter baumannii strain CFSAN093705

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: FQZ18_RS02320
• Protein ID: WP_000607077.1
• Coordinates: 473868..474257 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: FQZ18_RS02315
• Protein ID: WP_011860336.1
• Coordinates: 473616..473861 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FQZ18_RS02295	469120..470127	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
FQZ18_RS02300	470146..470523	+	378	WP_001216380.1	50S ribosomal protein L17	-
FQZ18_RS02305	470705..472195	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
FQZ18_RS02310	472244..473416	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
FQZ18_RS02315	473616..473861	+	246	WP_011860336.1	succinate dehydrogenase assembly factor 2	Antitoxin
FQZ18_RS02320	473868..474257	+	390	WP_000607077.1	membrane protein	Toxin
FQZ18_RS02325	475027..476112	+	1086	WP_000049106.1	hypothetical protein	-
FQZ18_RS02330	476190..476756	+	567	WP_000651538.1	rhombosortase	-
FQZ18_RS02335	476944..479139	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T172687 WP_000607077.1 NZ_CP061525:473868-474257 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T172687 NZ_CP079865:c2498280-2498023 [Mycobacterium sp. SMC-8]
GTGAGACACATCAACGTCGACCCCGACGCCTGGGAGGATTTCCTGTTCTGGCTGGCGTCCGACCGCAAGACGGCTCGACG
GATCACGAGACTGATCGGAGAGATCCAACGCGATCCGTTCGGGGGGATCGGCAAACCCGAACCGCTCAAGGGCGAACTGT
CCGGATACTGGTCTCGGCGTATAGACGACGAACACCGGCTCGTCTACCGAGCAGACGATCACCAAGTCACGATATTGAAG
GCCCGGTACCACTACTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9842.27 Da
• Isoelectric Point: 4.9001

>AT172687 WP_011860336.1 NZ_CP061525:473616-473861 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT172687 NZ_CP079865:c2498561-2498277 [Mycobacterium sp. SMC-8]
ATGAGCATCAGTGCCAGCGAGGCGCGCCAGCGCCTCTTTCCACTCCTCGAACAAGTCAACACCGACCATGAGCCGGTACG
CATCACCTCCAGGGCAGGAGATGCGGTGCTGATGTCCGCTGACGACTACGACTCGTGGCAGGAAACGGTCTACCTACTGC
GCTCACCCGAGAATGCCCGCCGACTCATGGAGGCCGTCGCCCGCGACAAGGCCGGCCGGCACGCAACCCCACACCTCACC
AAGTCGATCGACGAACTTCAGGAGATGGCCGGCGGCGAGGAGTGA