Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/-
Location 448104..448745 Replicon chromosome
Accession NZ_CP061523
Organism Acinetobacter baumannii strain CFSAN093706

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FQZ16_RS02175 Protein ID WP_000607077.1
Coordinates 448356..448745 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FQZ16_RS02170 Protein ID WP_011860336.1
Coordinates 448104..448349 (+) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQZ16_RS02150 443608..444615 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
FQZ16_RS02155 444634..445011 + 378 WP_001216380.1 50S ribosomal protein L17 -
FQZ16_RS02160 445193..446683 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
FQZ16_RS02165 446732..447904 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
FQZ16_RS02170 448104..448349 + 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
FQZ16_RS02175 448356..448745 + 390 WP_000607077.1 membrane protein Toxin
FQZ16_RS02180 449515..450600 + 1086 WP_000049106.1 hypothetical protein -
FQZ16_RS02185 450678..451244 + 567 WP_000651538.1 rhombosortase -
FQZ16_RS02190 451432..453627 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(6-78)


Sequences


Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T172684 WP_000607077.1 NZ_CP061523:448356-448745 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T172684 NZ_CP079863:c3783380-3782805 [Mycobacterium sp. SMC-2]
ATGAAGCGACTGGACCTCGTCGTCGGCCCGAACGGCGCCGGCAAGTCGACGTTCATCGCGTTGACGTTGGCGCCGTTGTT
GCCGCGCAGCGTGTGCGTCAACGCCGACGAGATCGCAAAGCAGCGGTGGCCCGATGACCCACTTGCGCACGCCTACGATG
CGGCGCGGGTCGCCGCAGACACCCGCGCCAAGTTGATCGAGGCGGGCGTGTCGTTCATCGCCGAGACCGTGTTCTCCCAT
CCGTCGAAGCTGGACCTGATCCGCTCCGCTCACGATGCGGGCTACACCATCGCCTTGCACGTGGTACTGATCCCTGAGGA
CCTCGCCGTCGAACGCGTGAAGCGGCGCGTCCGCCACGGCGGTCACGACGTGCCCGAGGGCAAGATCCGCGAGCGGCACC
GGCGATTATGGCAATTCGTGGCCGACGCGGTCCAAATCGCGGACACCGCAACCGTCTACGACAATTCGCGGCGCGCGGGA
CCCCGAATCGTCGCGCAATTCACGGCGGGCACGGTCATCGGGGCACCGACGTTGCCGGCTTGGGCGTCCGAACAGCTCCG
CCGTTGGCCAGCCTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT172684 WP_011860336.1 NZ_CP061523:448104-448349 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT172684 NZ_CP079863:c3783792-3783403 [Mycobacterium sp. SMC-2]
ATGACTAACGTCGCCGATCGCGTCACCAGGGTCGCCGCCGACCTGATGGACAGCGCCGCCGCCGAAGGGGCTCGCCAGAG
CCGCTCGGCCAAGCAGCAACTCGACCACTGGGCCCGGGTGGGCCGCGCGGTGTCGAGCCATCAGACGGCCTCCCGCCACC
GTGTCGAGGCCGCGCTGGCCGGCCGTCTGGATACCAACGACCTGTCCGAGGACGAGGGCCTCGTGTTCAACGCGGAGATC
TCGGCCGCCATCGAGGAGTCCTTGGCCACCACCAATTACGGTGACACCCTCGCAGCGCAGGGCATCACGACGGTGGCGCT
CAACGACGACGGCGAGATCATCGAGTACAGGCCCGACGGCACAACCGCGGTGGTCGACGCCGACCGATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References