Detailed information of TA system TA172673

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 448084..448725
• Replicon: chromosome
• Accession: NZ_CP061517
• Organism: Acinetobacter baumannii strain CFSAN093709

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: FRO58_RS02175
• Protein ID: WP_000607077.1
• Coordinates: 448336..448725 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: FRO58_RS02170
• Protein ID: WP_011860336.1
• Coordinates: 448084..448329 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FRO58_RS02150	443588..444595	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
FRO58_RS02155	444614..444991	+	378	WP_001216380.1	50S ribosomal protein L17	-
FRO58_RS02160	445173..446663	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
FRO58_RS02165	446712..447884	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
FRO58_RS02170	448084..448329	+	246	WP_011860336.1	succinate dehydrogenase assembly factor 2	Antitoxin
FRO58_RS02175	448336..448725	+	390	WP_000607077.1	membrane protein	Toxin
FRO58_RS02180	449495..450580	+	1086	WP_000049106.1	hypothetical protein	-
FRO58_RS02185	450658..451224	+	567	WP_000651538.1	rhombosortase	-
FRO58_RS02190	451412..453607	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T172673 WP_000607077.1 NZ_CP061517:448336-448725 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T172673 NZ_CP079860:c1221273-1220983 [Vibrio neptunius]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAAAAGCTTGGCTCTACTCTGCAACAACAATTTAA
GAAAAAGCTGATAGAACGCTTAGATAACCCACATGTTCCCGCTTCAAAGCTTTCTGGATCTGACAACATGTATAAAATTA
AGTTGCGTCAATCGGGCTACCGTCTAGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCTTAGCAGTCGGAAAA
CGAGAACGTAGCAATGTTTACCGTAAAGCCATGAAAAGGTTAGATGATTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9842.27 Da
• Isoelectric Point: 4.9001

>AT172673 WP_011860336.1 NZ_CP061517:448084-448329 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT172673 NZ_CP079860:c1221511-1221263 [Vibrio neptunius]
ATGACCACTAGAATTTTAGCCGATGTTGCTGCAAGCATTACCGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTATGGTGAACCTGTTGCTGTATTAAACCGAAATGAGCCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTAGCTCTCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA