Detailed information of TA system TA172666

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 490653..491155
• Replicon: chromosome
• Accession: NZ_CP061513
• Organism: Morganella morganii strain GDMM86

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IDH72_RS02255
• Protein ID: WP_143970178.1
• Coordinates: 490653..490907 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: IDH72_RS02260
• Protein ID: WP_046894052.1
• Coordinates: 490904..491155 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IDH72_RS02235	485892..486551	-	660	WP_143970177.1	YtjB family periplasmic protein	-
IDH72_RS02240	486653..487630	+	978	WP_112548193.1	phosphoserine phosphatase	-
IDH72_RS02245	487656..489044	+	1389	WP_015422438.1	DNA repair protein RadA	-
IDH72_RS02250	489057..490319	+	1263	WP_004237101.1	multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR	-
IDH72_RS02255	490653..490907	-	255	WP_143970178.1	Txe/YoeB family addiction module toxin	Toxin
IDH72_RS02260	490904..491155	-	252	WP_046894052.1	YoeB-YefM toxin-antitoxin system antitoxin YefM	Antitoxin
IDH72_RS02265	491293..492960	-	1668	WP_032099035.1	energy-dependent translational throttle protein EttA	-
IDH72_RS02270	493174..493599	-	426	WP_143970179.1	Exc2 family lipoprotein	-
IDH72_RS02275	494180..496105	+	1926	WP_143970180.1	murein transglycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10033.39 Da
• Isoelectric Point: 10.0255

>T172666 WP_143970178.1 NZ_CP061513:c490907-490653 [Morganella morganii]
MTLTFSSQAWEDYLYWQNTDKKTLRRINELIKAAQRTPFTGIGKPEPLKNNLSGWWSRRITEEHRLVYRVTNQGVEVAAC
RYHY

Nucleotide

• Length: 255 bp

>T172666 NZ_CP079855:929232-929591 [Agrobacterium fabrum]
ATGGTCCGCAACCAGATCCCCAAGCGCGGCGACGTTTATCTGGTTGATCTAAACCCTGTCGTAGGCAGCGAAATCAAGGA
CGAACATCGCTGTGTCGTCATCACGCCCAGAGAAATTAACGCGGTCGGACTCTGTCTCGTCGTCCCGGTGACCACCGGCG
GCATGTTTACGCGCAAGGCAGGGCTTGCCGTAAATATATCCGGCCACAAGACAACGGGCGTCGCTTTGTGCAATCAGGTG
AGAAGCATGGATATCGTCGCCCGGGTTGCCCAGAAGAAAGCGAAATATATCGAAACCCTCGATGATGCGACGATCGATGA
AATCGCCGGGCGCGTCATCAGCATGATCGATCCAGCTTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9433.77 Da
• Isoelectric Point: 4.7863

>AT172666 WP_046894052.1 NZ_CP061513:c491155-490904 [Morganella morganii]
MKTLTYSEVRQNLTAAMNETVDDRIPILITRQKGTACVLLSLDEYQSLEETAYLMRSPNNARRLMDSIDELNAGKGLKKE
INE

Nucleotide

• Length: 252 bp

>AT172666 NZ_CP079855:928966-929232 [Agrobacterium fabrum]
ATGACCGTGACCACGAAAATAAGACGCCAGGGCGGCGCGGCGGTGATGACGATCCCGCCCGCTCTTTTGAAGATGCTGGG
GCTGGAAATCGGTGAGCAACTGACGCTCGAGGTCGATAATGGCGCTCTGGTGGCAAGCCCGGTTCGACTGGAAAAGAAAC
GCTTCACGCTGGCCGAATTACTGGATGGTGCAGAGGAAGTGGCAGCTCTAAACGCCAGGGAGCGGGCGTGGGACACAGCG
CCTCCTGTCGGCAAAGAAGCGTTGTGA