Detailed information of TA system TA172661

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 1325334..1325730
• Replicon: chromosome
• Accession: NZ_CP061497
• Organism: Thermomonas sp. XSG

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: -
• Locus tag: ICG51_RS06275
• Protein ID: WP_190282127.1
• Coordinates: 1325334..1325462 (-)
• Length: 43 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: ICG51_RS06280
• Protein ID: WP_190282128.1
• Coordinates: 1325578..1325730 (-)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICG51_RS06250	1321386..1322264	-	879	WP_190282124.1	aspartyl protease family protein	-
ICG51_RS06255	1322377..1322763	+	387	WP_190282125.1	VOC family protein	-
ICG51_RS06260	1322764..1323057	-	294	WP_190282388.1	hypothetical protein	-
ICG51_RS06265	1323072..1324391	-	1320	WP_190282126.1	tryptophan--tRNA ligase	-
ICG51_RS06270	1324551..1325294	+	744	WP_190282389.1	hypothetical protein	-
ICG51_RS06275	1325334..1325462	-	129	WP_190282127.1	entericidin A/B family lipoprotein	Toxin
ICG51_RS06280	1325578..1325730	-	153	WP_190282128.1	entericidin A/B family lipoprotein	Antitoxin
ICG51_RS06285	1325840..1326319	-	480	WP_190282129.1	DUF421 domain-containing protein	-
ICG51_RS06290	1326715..1329513	-	2799	WP_190282130.1	DNA polymerase I	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (22-40)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 43 a.a.
• Molecular weight: 4294.23 Da
• Isoelectric Point: 9.4064

>T172661 WP_190282127.1 NZ_CP061497:c1325462-1325334 [Thermomonas sp. XSG]
MKQMKMALVALACLAFLAGCNTIAGAGKDIQKAGEKIEGAVK

Nucleotide

• Length: 129 bp

>T172661 NZ_CP079839:c2681720-2681502 [Salmonella enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAACTATCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTTTACGACAAGATCCCTTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5435.57 Da
• Isoelectric Point: 8.2766

>AT172661 WP_190282128.1 NZ_CP061497:c1325730-1325578 [Thermomonas sp. XSG]
MKRLIALLMLVMFSSMVLTACNTVAGAGKDVQKAGEKVEEKAQDCKDMKC

Nucleotide

• Length: 153 bp

>AT172661 NZ_CP079839:c2682122-2681748 [Salmonella enterica]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTTCGCTGTTTCGTCAACGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA