Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3260307..3260452 Replicon chromosome
Accession NZ_CP061404
Organism Klebsiella pneumoniae strain NU-CRE055

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3260314..3260416 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3260307..3260452 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCV81_RS16230 3255839..3257272 + 1434 WP_040236949.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HCV81_RS16235 3257388..3257627 + 240 WP_002911393.1 YebV family protein -
HCV81_RS16240 3257725..3257916 + 192 WP_002911395.1 YebW family protein -
HCV81_RS16245 3257913..3258566 - 654 WP_020802220.1 protein-serine/threonine phosphatase -
HCV81_RS16250 3258723..3259691 + 969 WP_072158545.1 VirK/YbjX family protein -
HCV81_RS16255 3259796..3259939 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3260307..3260452 + 146 - - Antitoxin
- 3260314..3260416 - 103 - - Toxin
HCV81_RS16260 3260575..3260913 - 339 WP_002911404.1 YebY family protein -
HCV81_RS16265 3260930..3261799 - 870 WP_057774489.1 copper homeostasis membrane protein CopD -
HCV81_RS16270 3261803..3262177 - 375 WP_004151448.1 CopC domain-containing protein YobA -
HCV81_RS16275 3262290..3262520 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HCV81_RS16280 3262599..3263258 + 660 WP_002911407.1 exodeoxyribonuclease X -
HCV81_RS16285 3263262..3265322 - 2061 WP_040237002.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T172633 NZ_CP061404:c3260416-3260314 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT172633 NZ_CP061404:3260307-3260452 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References