Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2112736..2112881 | Replicon | chromosome |
| Accession | NZ_CP061396 | ||
| Organism | Klebsiella pneumoniae strain NU-CRE193 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2112772..2112874 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2112736..2112881 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HCV83_RS10315 | 2107866..2109926 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| HCV83_RS10320 | 2109930..2110589 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| HCV83_RS10325 | 2110668..2110898 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| HCV83_RS10330 | 2111011..2111385 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| HCV83_RS10335 | 2111389..2112258 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| HCV83_RS10340 | 2112275..2112613 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2112736..2112881 | - | 146 | - | - | Antitoxin |
| - | 2112772..2112874 | + | 103 | - | - | Toxin |
| HCV83_RS10345 | 2113309..2114289 | - | 981 | WP_000019473.1 | IS5-like element ISKpn26 family transposase | - |
| HCV83_RS10350 | 2114449..2114592 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| HCV83_RS10355 | 2114697..2115665 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| HCV83_RS10360 | 2115822..2116475 | + | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| HCV83_RS10365 | 2116472..2116663 | - | 192 | WP_002911395.1 | YebW family protein | - |
| HCV83_RS10370 | 2116761..2117000 | - | 240 | WP_002911393.1 | YebV family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 2113309..2114289 | 980 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T172594 NZ_CP061396:2112772-2112874 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT172594 NZ_CP061396:c2112881-2112736 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
