Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2081800..2081945 Replicon chromosome
Accession NZ_CP061389
Organism Klebsiella pneumoniae strain NU-CRE195

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2081836..2081938 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2081800..2081945 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCV84_RS10335 2076930..2078990 + 2061 WP_004151449.1 oligopeptidase B -
HCV84_RS10340 2078994..2079653 - 660 WP_004180433.1 exodeoxyribonuclease X -
HCV84_RS10345 2079732..2079962 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HCV84_RS10350 2080075..2080449 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HCV84_RS10355 2080453..2081322 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HCV84_RS10360 2081339..2081677 + 339 WP_002911404.1 YebY family protein -
- 2081800..2081945 - 146 - - Antitoxin
- 2081836..2081938 + 103 - - Toxin
HCV84_RS10365 2082314..2082457 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HCV84_RS10370 2082562..2083530 - 969 WP_004151446.1 VirK/YbjX family protein -
HCV84_RS10375 2083687..2084340 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HCV84_RS10380 2084337..2084528 - 192 WP_002911395.1 YebW family protein -
HCV84_RS10385 2084626..2084865 - 240 WP_002911393.1 YebV family protein -
HCV84_RS10390 2084981..2086414 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T172574 NZ_CP061389:2081836-2081938 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT172574 NZ_CP061389:c2081945-2081800 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References