Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3921143..3921288 Replicon chromosome
Accession NZ_CP061385
Organism Klebsiella pneumoniae strain NU-CRE213

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3921150..3921252 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3921143..3921288 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCV85_RS19470 3916675..3918108 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HCV85_RS19475 3918224..3918463 + 240 WP_002911393.1 YebV family protein -
HCV85_RS19480 3918561..3918752 + 192 WP_002911395.1 YebW family protein -
HCV85_RS19485 3918749..3919402 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
HCV85_RS19490 3919559..3920527 + 969 WP_004151446.1 VirK/YbjX family protein -
HCV85_RS19495 3920632..3920775 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3921143..3921288 + 146 - - Antitoxin
- 3921150..3921252 - 103 - - Toxin
HCV85_RS19500 3921411..3921749 - 339 WP_002911404.1 YebY family protein -
HCV85_RS19505 3921766..3922635 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HCV85_RS19510 3922639..3923013 - 375 WP_004151448.1 CopC domain-containing protein YobA -
HCV85_RS19515 3923126..3923356 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HCV85_RS19520 3923435..3924094 + 660 WP_002911407.1 exodeoxyribonuclease X -
HCV85_RS19525 3924098..3926158 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T172557 NZ_CP061385:c3921252-3921150 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT172557 NZ_CP061385:3921143-3921288 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References