Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 5766822..5767525 Replicon chromosome
Accession NZ_CP061379
Organism Bradyrhizobium genosp. B strain BDV5040

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IC761_RS27155 Protein ID WP_195799751.1
Coordinates 5767100..5767525 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IC761_RS27150 Protein ID WP_195799750.1
Coordinates 5766822..5767103 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC761_RS27130 5761966..5762868 - 903 WP_195799746.1 sugar ABC transporter permease -
IC761_RS27135 5762868..5763953 - 1086 WP_195799747.1 ABC transporter ATP-binding protein -
IC761_RS27140 5763967..5765043 - 1077 WP_195799748.1 ABC transporter ATP-binding protein -
IC761_RS27145 5765040..5766590 - 1551 WP_195799749.1 glycerol-3-phosphate dehydrogenase -
IC761_RS27150 5766822..5767103 + 282 WP_195799750.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IC761_RS27155 5767100..5767525 + 426 WP_195799751.1 type II toxin-antitoxin system VapC family toxin Toxin
IC761_RS27160 5767530..5768375 - 846 WP_195799752.1 DeoR/GlpR family DNA-binding transcription regulator -
IC761_RS27165 5768468..5769154 - 687 WP_195799753.1 HAD-IA family hydrolase -
IC761_RS27170 5769309..5769761 + 453 WP_195799754.1 nuclear transport factor 2 family protein -
IC761_RS27175 5769942..5770133 - 192 WP_195799755.1 hypothetical protein -
IC761_RS27180 5770352..5770762 - 411 WP_195799756.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(14-75)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15584.87 Da        Isoelectric Point: 4.9102

>T172528 WP_195799751.1 NZ_CP061379:5767100-5767525 [Bradyrhizobium genosp. B]
VNLLLDTNVLSEVQRPMPSPKVLAWLDTIDEDRAFISVASIAELRRGIALLEDGRRRTALATWLAHDLPERFAGRMLPID
HAVAERWGDLMAESRRSGVALSVIDGFFAATALANGLTLVTRNVKDFAAFGVQLFNPWDDV

Download         Length: 426 bp

>T172528 NZ_CP079777:41374-41754 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATAGCGCTTCATGATGCGAATATAAGCCGCTACGGCGGCCTGCCTGGCATGTC
AGATCCGGGCAGGGCAGAGGCCATTATCGGGAGAGTCCAGGCCAGAGTTGTGTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGCTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACCGTAGGGACTGCGACTGG
CGAGATATCTGTATCTACTGTCGCCGCCACGTTACGTAGATTGTATGGTTCTGCGGAGTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10212.53 Da        Isoelectric Point: 6.8802

>AT172528 WP_195799750.1 NZ_CP061379:5766822-5767103 [Bradyrhizobium genosp. B]
MTDHSTAPDSPATDTWTLANAKARLSEVIDRAQTGPQIITRHGKPNAVVVSAEEWSRKTARKGTLAEFLLASPLHGADLK
LERMHDVPRDEMP

Download         Length: 282 bp

>AT172528 NZ_CP079777:41153-41374 [Escherichia coli]
ATGCAATCCATTAACTTCCGTACCGCGCGCGGCAACCTTTCTGAAGTGCTCAACAATGTTGAAGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGTGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTCGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References