Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1179164..1179803 Replicon chromosome
Accession NZ_CP061379
Organism Bradyrhizobium genosp. B strain BDV5040

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag IC761_RS05635 Protein ID WP_195802298.1
Coordinates 1179510..1179803 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag IC761_RS05630 Protein ID WP_195802297.1
Coordinates 1179164..1179505 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC761_RS05600 1174204..1174650 - 447 WP_195802291.1 GNAT family N-acetyltransferase -
IC761_RS05605 1174650..1175678 - 1029 WP_195802292.1 peptidoglycan -binding protein -
IC761_RS05610 1175715..1176080 - 366 WP_195802293.1 VOC family protein -
IC761_RS05615 1176097..1177122 - 1026 WP_195802294.1 flagellar motor protein MotA -
IC761_RS05620 1177302..1178123 + 822 WP_195802295.1 DUF1295 domain-containing protein -
IC761_RS05625 1178120..1179148 + 1029 WP_195802296.1 cyclopropane-fatty-acyl-phospholipid synthase family protein -
IC761_RS05630 1179164..1179505 - 342 WP_195802297.1 putative addiction module antidote protein Antitoxin
IC761_RS05635 1179510..1179803 - 294 WP_195802298.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IC761_RS05640 1180179..1181369 + 1191 WP_195802299.1 efflux RND transporter periplasmic adaptor subunit -
IC761_RS05645 1181376..1184531 + 3156 WP_195802300.1 multidrug efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10574.28 Da        Isoelectric Point: 10.3378

>T172526 WP_195802298.1 NZ_CP061379:c1179803-1179510 [Bradyrhizobium genosp. B]
VVDVVQTEAFRGWLAGLRDRRAVARIASRIALIERGALGDVKSLGAGLSEFRIDYGPGYRLYAAQRGAAMVILLCGGDKR
KQDADIKRARAMLAELE

Download         Length: 294 bp

>T172526 NZ_CP079776:c6098-5577 [Escherichia coli]
GTGAGCAATACGACGATCGAGATTTTCTCTGGAGAGAAAGATTATGATCTAAACGGTTTTGATTGCGGCGAAGAGTCGCT
AAACGCATTTTTGACCAACCACTTAAAAAGACAGCATGAGGGAAAAATTCTTCGCGCTTATGTGCTTTGCACTAAAGAAG
AAATACCAAAGGTATTAGGTTATTACACTTTGTCAGGCAGCTGCTTTGAGAAAGAAACCTTACCTTCAAAGAGTCAGCAA
AAGAAAGTGCCTTATCGGAATGTCCCAAGTATCACTTTAGGCAGACTGGCTTTGGACAAATCTCTTCAAGGTCAGGGGCT
TGGCTCAATGCTTGTAACTCACGCAATGCGTGTTGTGTACAATGCATCTCTTGCGGTAGGCATTCATGGGCTTTTCGTTG
AGGCGTTGAACGATAAAGCCAGGGCGTTTTATAAAAGTTTGGGCTTTATCCAGCTGGTTGGTAACAACGATCGTTCTTTG
TTCTATCCAACAAAATCTATCGAAAAATTGTTCGAAGAATAA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 11953.81 Da        Isoelectric Point: 10.7257

>AT172526 WP_195802297.1 NZ_CP061379:c1179505-1179164 [Bradyrhizobium genosp. B]
MALKTTPFDAAEYLDTPEAQAEFITAALETGDAAFIRDAVNIVARARGMSEIAKSAGLSREGLYKALGEAGNPEFSTMLG
VLRALGLGLTARPLPRKPGKPRRSAKPRARKAA

Download         Length: 342 bp

>AT172526 NZ_CP079776:c6375-6106 [Escherichia coli]
ATGTCCGCACTGAAAAAGCAGCGCATCGATTTGAGATTAACCGATGACGATAAAAGCATCATCGAGGAAGCTGCCGCAAT
GTCTAACCAGAGCATTACCCAGTTCATGGTTAGCAGTGCATCCGAACGTGCCGTGAAGGTGATAGAGCAACACCGTAGAC
TGGTTCTAAGTGAAGAGTCCTGGAATCTGGTTATGGATGCTATAAGCAATCCTCCGGCACCGAACGACAAGCTGAAACGA
GCTGCCAATCGTCTGAAAAGCATGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References