Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2747915..2748265 Replicon chromosome
Accession NZ_CP061375
Organism Xanthomonas oryzae pv. oryzae strain IXO608

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO608_RS12910 Protein ID WP_011257368.1
Coordinates 2747915..2748049 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO608_RS12915 Protein ID WP_011407410.1
Coordinates 2748113..2748265 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO608_RS12895 (IXO608_012780) 2744929..2745873 - 945 WP_041181936.1 MBL fold metallo-hydrolase -
IXO608_RS12900 (IXO608_012785) 2746004..2747293 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO608_RS12905 (IXO608_012790) 2747462..2747671 - 210 WP_011407411.1 CsbD family protein -
IXO608_RS12910 (IXO608_012795) 2747915..2748049 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO608_RS12915 (IXO608_012800) 2748113..2748265 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO608_RS12920 (IXO608_012805) 2748373..2749296 - 924 WP_011407409.1 arginase -
IXO608_RS12925 2749618..2749836 + 219 Protein_2464 hypothetical protein -
IXO608_RS12930 (IXO608_012810) 2749828..2750292 + 465 Protein_2465 hypothetical protein -
IXO608_RS12935 2750289..2750831 + 543 Protein_2466 GTPase -
IXO608_RS12940 (IXO608_012825) 2751311..2751994 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T172513 WP_011257368.1 NZ_CP061375:c2748049-2747915 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T172513 NZ_CP079772:c2939558-2939208 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT172513 WP_011407410.1 NZ_CP061375:c2748265-2748113 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT172513 NZ_CP079772:c2939803-2939552 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References