Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 2099344..2100089 Replicon chromosome
Accession NZ_CP061375
Organism Xanthomonas oryzae pv. oryzae strain IXO608

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag IXO608_RS09760 Protein ID WP_199285672.1
Coordinates 2099344..2099673 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag IXO608_RS09765 Protein ID WP_011407754.1
Coordinates 2099670..2100089 (+) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO608_RS09730 (IXO608_009615) 2094476..2095147 + 672 WP_011407759.1 class I SAM-dependent methyltransferase -
IXO608_RS09740 (IXO608_009625) 2095449..2096240 - 792 WP_011407758.1 polysaccharide deacetylase family protein -
IXO608_RS09745 (IXO608_009630) 2096286..2097212 + 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
IXO608_RS09750 (IXO608_009635) 2097544..2097879 + 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
IXO608_RS09755 (IXO608_009640) 2097923..2099241 - 1319 Protein_1868 IS701 family transposase -
IXO608_RS09760 (IXO608_009645) 2099344..2099673 + 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
IXO608_RS09765 (IXO608_009650) 2099670..2100089 + 420 WP_011407754.1 macro domain-containing protein Antitoxin
IXO608_RS09770 (IXO608_009655) 2100141..2101109 + 969 WP_011258188.1 IS5-like element ISXo1 family transposase -
IXO608_RS09775 (IXO608_009660) 2101244..2101900 + 657 WP_075246166.1 phosphate phosphatase -
IXO608_RS09780 (IXO608_009665) 2101938..2103173 - 1236 WP_258691319.1 ISL3-like element ISXoo13 family transposase -
IXO608_RS09785 (IXO608_009670) 2103475..2103801 + 327 Protein_1874 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 2097923..2103173 5250


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-108)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T172512 WP_199285672.1 NZ_CP061375:2099344-2099673 [Xanthomonas oryzae pv. oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T172512 NZ_CP079772:2531933-2532211 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATGCTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT172512 WP_011407754.1 NZ_CP061375:2099670-2100089 [Xanthomonas oryzae pv. oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT172512 NZ_CP079772:2531670-2531930 [Escherichia coli]
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References