Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 3553718..3554258 Replicon chromosome
Accession NZ_CP061369
Organism Komagataeibacter rhaeticus strain ENS9b

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag ICJ78_RS16345 Protein ID WP_039998565.1
Coordinates 3553959..3554258 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A858JM77
Locus tag ICJ78_RS16340 Protein ID WP_007397371.1
Coordinates 3553718..3553972 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICJ78_RS16325 3548909..3550021 - 1113 WP_007397379.1 Fic family protein -
ICJ78_RS16330 3550500..3552035 + 1536 WP_139064268.1 hypothetical protein -
ICJ78_RS16335 3552032..3553453 + 1422 WP_166498174.1 hypothetical protein -
ICJ78_RS16340 3553718..3553972 + 255 WP_007397371.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
ICJ78_RS16345 3553959..3554258 + 300 WP_039998565.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ICJ78_RS16350 3554285..3554557 - 273 WP_007397369.1 DUF2274 domain-containing protein -
ICJ78_RS16355 3554554..3555762 - 1209 WP_007397368.1 TrbI/VirB10 family protein -
ICJ78_RS16360 3555759..3556760 - 1002 WP_039998564.1 P-type conjugative transfer protein TrbG -
ICJ78_RS16365 3556757..3557038 - 282 Protein_3220 conjugal transfer protein TrbF -
ICJ78_RS16370 3557256..3557411 - 156 Protein_3221 DUF736 family protein -
ICJ78_RS16375 3557410..3558849 - 1440 Protein_3222 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3495259..3567945 72686


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-92)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11703.42 Da        Isoelectric Point: 6.8441

>T172508 WP_039998565.1 NZ_CP061369:3553959-3554258 [Komagataeibacter rhaeticus]
MPTCRKTRLAEDDIVNIYMQGVRDFGPRQAEIYHAGLSDAFDLIASHPQLAPERHEFDPPIRLHRHRAHHILYLIDDDGV
LIVRVLPRLRRWERLMETD

Download         Length: 300 bp

>T172508 NZ_CP079772:1549589-1549696 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9187.24 Da        Isoelectric Point: 6.4618

>AT172508 WP_007397371.1 NZ_CP061369:3553718-3553972 [Komagataeibacter rhaeticus]
MATMNVSLPDPMKEWVEAQAKTGRYSNASDYVRDLIRRDQEARAAHDEVQAHITAGLRSGVGTRSMKQLLQDARAAAGTT
DADL

Download         Length: 255 bp

>AT172508 NZ_CP079772:c1549542-1549476 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A858JM77

References