Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 3504518..3505059 Replicon chromosome
Accession NZ_CP061369
Organism Komagataeibacter rhaeticus strain ENS9b

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag ICJ78_RS16100 Protein ID WP_083824409.1
Coordinates 3504760..3505059 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A181C5T9
Locus tag ICJ78_RS16095 Protein ID WP_039998678.1
Coordinates 3504518..3504760 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICJ78_RS16065 3500726..3500959 - 234 WP_099963248.1 hypothetical protein -
ICJ78_RS16070 3501000..3501700 + 701 Protein_3161 hypothetical protein -
ICJ78_RS16075 3501675..3502046 + 372 WP_172459683.1 hypothetical protein -
ICJ78_RS16080 3502414..3502572 + 159 WP_156953886.1 hypothetical protein -
ICJ78_RS16085 3502633..3503783 + 1151 WP_085948976.1 IS3 family transposase -
ICJ78_RS16090 3503808..3503979 - 172 Protein_3165 transposase -
ICJ78_RS16095 3504518..3504760 + 243 WP_039998678.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
ICJ78_RS16100 3504760..3505059 + 300 WP_083824409.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3495259..3567945 72686
- flank IS/Tn - - 3502633..3502899 266


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11334.87 Da        Isoelectric Point: 7.3581

>T172507 WP_083824409.1 NZ_CP061369:3504760-3505059 [Komagataeibacter rhaeticus]
MRFLLRPAAQADLSAIWDYSAQRWGTTQADDYVRAIGRACQDLADGTRHGRTADDIREGYLKMLVGSHLLFFRVNENGFI
DVIRILHGRMDPTRHMTDV

Download         Length: 300 bp

>T172507 NZ_CP079772:1549054-1549161 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8829.82 Da        Isoelectric Point: 4.7962

>AT172507 WP_039998678.1 NZ_CP061369:3504518-3504760 [Komagataeibacter rhaeticus]
MARNTSISLGDHFADFVDQQVKGGRYGSASDVVRAGLRILEERETRLETLRSALIDGEQSGAAEPFDIEDFLAAKAKQFR

Download         Length: 243 bp

>AT172507 NZ_CP079772:c1549007-1548941 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A181C5T9

References