172497

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpIK/PemK(toxin)
Location 1897415..1897976 Replicon chromosome
Accession NZ_CP061368
Organism Wenzhouxiangella sp. AB-CW3

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag IC757_RS08265 Protein ID WP_190976847.1
Coordinates 1897415..1897753 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name chpI Uniprot ID -
Locus tag IC757_RS08270 Protein ID WP_190976848.1
Coordinates 1897740..1897976 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC757_RS08225 1892452..1893168 - 717 WP_190976840.1 Crp/Fnr family transcriptional regulator -
IC757_RS08230 1893174..1893896 - 723 WP_190976986.1 Crp/Fnr family transcriptional regulator -
IC757_RS08235 1894410..1894592 + 183 WP_190976841.1 hypothetical protein -
IC757_RS08240 1894594..1895427 + 834 WP_190976842.1 ATP-binding protein -
IC757_RS08245 1895442..1895648 + 207 WP_190976843.1 hypothetical protein -
IC757_RS08250 1895870..1896271 - 402 WP_190976844.1 DUF1801 domain-containing protein -
IC757_RS08255 1896345..1896695 - 351 WP_190976845.1 DUF2200 domain-containing protein -
IC757_RS08260 1896698..1897249 - 552 WP_190976846.1 DUF1579 family protein -
IC757_RS08265 1897415..1897753 - 339 WP_190976847.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
IC757_RS08270 1897740..1897976 - 237 WP_190976848.1 ChpI protein Antitoxin
IC757_RS08275 1898083..1898436 - 354 WP_190976849.1 hypothetical protein -
IC757_RS08280 1898639..1901707 - 3069 WP_190976850.1 DEAD/DEAH box helicase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12234.21 Da        Isoelectric Point: 12.1730

>T172497 WP_190976847.1 NZ_CP061368:c1897753-1897415 [Wenzhouxiangella sp. AB-CW3]
MKRGEIWWASLPEPTGSGPGFRRPVLVVQSNPFNSSRIATVVVAAITSNLRLSAAPGNARITKRESGLGKASVVNVSQVL
TLDRTRLTEQVRRLSEKRMLEIDQGLRVVLGL

Download         Length: 339 bp

>T172497 NZ_CP079770:4196459-4196755 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8738.84 Da        Isoelectric Point: 4.7906

>AT172497 WP_190976848.1 NZ_CP061368:c1897976-1897740 [Wenzhouxiangella sp. AB-CW3]
MKVAISVPDPVFQAAEQFAKERGIPRSQLFAEALEEYLAQHGPEAITAQLNRVHDSEKSKLDESFIRAQSAVLKDEAW

Download         Length: 237 bp

>AT172497 NZ_CP079770:4196757-4197152 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References