Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 183793..184295 Replicon chromosome
Accession NZ_CP061368
Organism Wenzhouxiangella sp. AB-CW3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IC757_RS00815 Protein ID WP_190975522.1
Coordinates 183793..184047 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IC757_RS00820 Protein ID WP_190975523.1
Coordinates 184044..184295 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC757_RS00785 178869..179171 - 303 WP_190975517.1 HigA family addiction module antidote protein -
IC757_RS00790 179171..179461 - 291 WP_190975518.1 type II toxin-antitoxin system RelE/ParE family toxin -
IC757_RS00795 179657..180130 + 474 WP_190976887.1 DUF4442 domain-containing protein -
IC757_RS00800 180093..181340 - 1248 WP_190975519.1 alpha/beta fold hydrolase -
IC757_RS00805 181483..182472 + 990 WP_190975520.1 zinc-dependent alcohol dehydrogenase family protein -
IC757_RS00810 182747..183760 + 1014 WP_190975521.1 NAD(P)-dependent alcohol dehydrogenase -
IC757_RS00815 183793..184047 - 255 WP_190975522.1 Txe/YoeB family addiction module toxin Toxin
IC757_RS00820 184044..184295 - 252 WP_190975523.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IC757_RS00825 184506..184973 + 468 WP_190975524.1 hypothetical protein -
IC757_RS00830 184970..186592 + 1623 WP_190975525.1 SWIM zinc finger family protein -
IC757_RS00835 186602..187099 - 498 WP_190975526.1 exonuclease -
IC757_RS00840 187292..188626 - 1335 WP_190976888.1 type II toxin-antitoxin system HipA family toxin -
IC757_RS00845 188616..188948 - 333 WP_190975527.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10065.71 Da        Isoelectric Point: 10.5637

>T172492 WP_190975522.1 NZ_CP061368:c184047-183793 [Wenzhouxiangella sp. AB-CW3]
VKICFHAHAWADYLYWQKADPKKLKRINELIRAIGRDPFKGVGKPEPLRGNWSGFWSRRIDRKHRLVYAVENDTLLIAQC
RFHY

Download         Length: 255 bp

>T172492 NZ_CP079770:c3008378-3008205 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9288.40 Da        Isoelectric Point: 4.6128

>AT172492 WP_190975523.1 NZ_CP061368:c184295-184044 [Wenzhouxiangella sp. AB-CW3]
MSTISYTDLRRRLASAMDQVNEDHAPLYITRQKGKGAVLLSADDYASIEETLYLMSSPRNAARLTEAIEGLRQGEGETRE
LIE

Download         Length: 252 bp

>AT172492 NZ_CP079770:c3008702-3008406 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGATT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References