Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3559881..3560115 | Replicon | chromosome |
| Accession | NZ_CP061367 | ||
| Organism | Shigella sonnei strain 6207 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3559882..3559985 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3559881..3560115 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IC759_RS18850 | 3556020..3556202 | + | 183 | Protein_3518 | host-nuclease inhibitor Gam family protein | - |
| IC759_RS18855 | 3556208..3557305 | + | 1098 | WP_001173292.1 | AAA family ATPase | - |
| IC759_RS18860 | 3557356..3557544 | + | 189 | WP_263452903.1 | DUF1187 family protein | - |
| - | 3557362..3557540 | - | 179 | NuclAT_1 | - | - |
| - | 3557362..3557540 | - | 179 | NuclAT_1 | - | - |
| - | 3557362..3557540 | - | 179 | NuclAT_1 | - | - |
| - | 3557362..3557540 | - | 179 | NuclAT_1 | - | - |
| IC759_RS18865 | 3557651..3557911 | + | 261 | WP_077447296.1 | excisionase | - |
| IC759_RS18870 | 3557940..3558637 | + | 698 | WP_229318984.1 | IS1-like element IS1A family transposase | - |
| IC759_RS18875 | 3558674..3559750 | + | 1077 | WP_001189101.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 3559881..3560115 | + | 235 | - | - | Antitoxin |
| - | 3559882..3559985 | - | 104 | - | - | Toxin |
| IC759_RS18880 | 3560143..3560484 | - | 342 | WP_000976476.1 | YebY family protein | - |
| IC759_RS18885 | 3560497..3561369 | - | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| IC759_RS18890 | 3561373..3561747 | - | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| IC759_RS18895 | 3561886..3562116 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| IC759_RS18900 | 3562218..3562874 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| IC759_RS18905 | 3562898..3563560 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | ipaH9.8 | 3545225..3560484 | 15259 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T172481 NZ_CP061367:c3559985-3559882 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT172481 NZ_CP061367:3559881-3560115 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
