Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3602864..3603009 Replicon chromosome
Accession NZ_CP061350
Organism Klebsiella pneumoniae strain ENT1988

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3602871..3602973 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3602864..3603009 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICN80_RS17375 3598397..3599830 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ICN80_RS17380 3599946..3600185 + 240 WP_002911393.1 YebV family protein -
ICN80_RS17385 3600283..3600474 + 192 WP_002911395.1 YebW family protein -
ICN80_RS17390 3600471..3601124 - 654 WP_004189273.1 protein-serine/threonine phosphatase -
ICN80_RS17395 3601281..3602249 + 969 WP_004151446.1 VirK/YbjX family protein -
ICN80_RS17400 3602354..3602497 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3602864..3603009 + 146 - - Antitoxin
- 3602871..3602973 - 103 - - Toxin
ICN80_RS17405 3603132..3603470 - 339 WP_002911404.1 YebY family protein -
ICN80_RS17410 3603487..3604356 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ICN80_RS17415 3604360..3604734 - 375 WP_004151448.1 CopC domain-containing protein YobA -
ICN80_RS17420 3604847..3605077 + 231 WP_002911406.1 DNA polymerase III subunit theta -
ICN80_RS17425 3605156..3605815 + 660 WP_002911407.1 exodeoxyribonuclease X -
ICN80_RS17430 3605819..3607879 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T172457 NZ_CP061350:c3602973-3602871 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT172457 NZ_CP061350:3602864-3603009 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References