Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2545579..2545850 Replicon chromosome
Accession NZ_CP061339
Organism Escherichia coli strain M00057

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2545617..2545720 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2545579..2545850 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC755_RS12180 2542736..2544175 + 1440 WP_188926226.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IC755_RS12185 2544293..2544529 + 237 WP_001295499.1 DUF1480 family protein -
IC755_RS12190 2544634..2544825 + 192 WP_001296140.1 YebW family protein -
IC755_RS12195 2544826..2545482 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 2545579..2545850 + 272 - - Antitoxin
- 2545617..2545720 - 104 - - Toxin
IC755_RS12200 2545878..2546219 - 342 WP_000976481.1 YebY family protein -
IC755_RS12205 2546232..2547104 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
IC755_RS12210 2547108..2547482 - 375 WP_000168743.1 CopC domain-containing protein YobA -
IC755_RS12215 2547621..2547851 + 231 WP_000916763.1 DNA polymerase III subunit theta -
IC755_RS12220 2547953..2548609 + 657 WP_000011654.1 carbon-nitrogen hydrolase family protein -
IC755_RS12225 2548633..2549295 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2528516..2553159 24643


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T172420 NZ_CP061339:c2545720-2545617 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT172420 NZ_CP061339:2545579-2545850 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References