Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2545340..2545611 Replicon chromosome
Accession NZ_CP061337
Organism Escherichia coli strain M11957

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2545378..2545481 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2545340..2545611 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC756_RS12180 2542497..2543936 + 1440 WP_188926226.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IC756_RS12185 2544054..2544290 + 237 WP_001295499.1 DUF1480 family protein -
IC756_RS12190 2544395..2544586 + 192 WP_001296140.1 YebW family protein -
IC756_RS12195 2544587..2545243 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 2545340..2545611 + 272 - - Antitoxin
- 2545378..2545481 - 104 - - Toxin
IC756_RS12200 2545639..2545980 - 342 WP_000976481.1 YebY family protein -
IC756_RS12205 2545993..2546865 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
IC756_RS12210 2546869..2547243 - 375 WP_000168743.1 CopC domain-containing protein YobA -
IC756_RS12215 2547382..2547612 + 231 WP_000916763.1 DNA polymerase III subunit theta -
IC756_RS12220 2547714..2548370 + 657 WP_000011654.1 carbon-nitrogen hydrolase family protein -
IC756_RS12225 2548394..2549056 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2528277..2552920 24643


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T172390 NZ_CP061337:c2545481-2545378 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT172390 NZ_CP061337:2545340-2545611 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References