Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1998739..1999010 Replicon chromosome
Accession NZ_CP061329
Organism Escherichia coli strain EC93

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1998869..1998972 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1998739..1999010 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8529_RS09565 1995294..1995956 - 663 WP_000944256.1 exodeoxyribonuclease X -
H8529_RS09570 1995980..1996636 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H8529_RS09575 1996738..1996968 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H8529_RS09580 1997107..1997481 + 375 WP_000204700.1 CopC domain-containing protein YobA -
H8529_RS09585 1997485..1998357 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
H8529_RS09590 1998370..1998711 + 342 WP_000976472.1 YebY family protein -
- 1998739..1999010 - 272 - - Antitoxin
- 1998869..1998972 + 104 - - Toxin
H8529_RS09595 1999107..1999763 + 657 WP_188214211.1 protein-serine/threonine phosphatase -
H8529_RS09600 1999764..1999955 - 192 WP_001296140.1 YebW family protein -
H8529_RS09605 2000060..2000296 - 237 WP_061892846.1 DUF1480 family protein -
H8529_RS09610 2000414..2001853 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T172356 NZ_CP061329:1998869-1998972 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT172356 NZ_CP061329:c1999010-1998739 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References