Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 263793..264324 Replicon chromosome
Accession NZ_CP061318
Organism Polynucleobacter sp. AP-Ainpum-60-G11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FD971_RS01405 Protein ID WP_215334325.1
Coordinates 263793..264083 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FD971_RS01410 Protein ID WP_215334326.1
Coordinates 264070..264324 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD971_RS01375 (FD971_01375) 258902..260041 - 1140 WP_215334321.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
FD971_RS01380 (FD971_01380) 260453..261079 + 627 WP_251368650.1 hypothetical protein -
FD971_RS01385 (FD971_01385) 261021..261416 + 396 WP_215334322.1 hypothetical protein -
FD971_RS01390 (FD971_01390) 261409..261957 + 549 WP_251368651.1 GspH/FimT family pseudopilin -
FD971_RS01395 (FD971_01395) 262005..263120 + 1116 WP_215334323.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
FD971_RS01400 (FD971_01400) 263175..263792 + 618 WP_215334324.1 riboflavin synthase -
FD971_RS01405 (FD971_01405) 263793..264083 - 291 WP_215334325.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FD971_RS01410 (FD971_01410) 264070..264324 - 255 WP_215334326.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FD971_RS01415 (FD971_01415) 264413..265153 - 741 WP_215334327.1 7-cyano-7-deazaguanine synthase QueC -
FD971_RS01420 (FD971_01420) 265184..265915 - 732 WP_215334329.1 tol-pal system protein YbgF -
FD971_RS01425 (FD971_01425) 265915..266412 - 498 WP_215334331.1 peptidoglycan-associated lipoprotein Pal -
FD971_RS01430 (FD971_01430) 266532..267839 - 1308 WP_251368652.1 Tol-Pal system beta propeller repeat protein TolB -
FD971_RS01435 (FD971_01435) 267843..268700 - 858 WP_215334333.1 cell envelope integrity protein TolA -
FD971_RS01440 (FD971_01440) 268720..269139 - 420 WP_215334334.1 ExbD/TolR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-72)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11148.15 Da        Isoelectric Point: 10.7713

>T172342 WP_215334325.1 NZ_CP061318:c264083-263793 [Polynucleobacter sp. AP-Ainpum-60-G11]
MKTYSLEFNVLALKEWQKLDNSVRSQFKKQLEKRIQNPRIASAKLHGDLDNFYKIKLAALGYRLVYEVIDHKLVVLIIAV
GKRNQSAVYKAASKRK

Download         Length: 291 bp

>T172342 NZ_CP079735:c2371692-2371516 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9269.90 Da        Isoelectric Point: 9.5955

>AT172342 WP_215334326.1 NZ_CP061318:c264324-264070 [Polynucleobacter sp. AP-Ainpum-60-G11]
MTITQTIHAKTTVSMTDLRRNPSKILEIAGDLPVAVLNHNKPEAYLLSAKAYEALLDLVDDLSLIKIIKARNSGKTVKVK
LEDL

Download         Length: 255 bp

>AT172342 NZ_CP079735:c2371470-2371054 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References