Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 1127231..1127762 Replicon chromosome
Accession NZ_CP061315
Organism Polynucleobacter sp. AP-Kolm-20A-A1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C2745_RS05610 Protein ID WP_215383401.1
Coordinates 1127231..1127512 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag C2745_RS05615 Protein ID WP_215383402.1
Coordinates 1127499..1127762 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2745_RS05595 (C2745_05595) 1123232..1124674 + 1443 WP_215383398.1 ATP-binding protein -
C2745_RS05600 (C2745_05600) 1124686..1125333 + 648 WP_215383399.1 response regulator -
C2745_RS05605 (C2745_05605) 1125361..1127139 - 1779 WP_215383400.1 ShlB/FhaC/HecB family hemolysin secretion/activation protein -
C2745_RS05610 (C2745_05610) 1127231..1127512 - 282 WP_215383401.1 type II toxin-antitoxin system YafQ family toxin Toxin
C2745_RS05615 (C2745_05615) 1127499..1127762 - 264 WP_215383402.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C2745_RS05620 (C2745_05620) 1127889..1129004 + 1116 WP_215383403.1 quinolinate synthase NadA -
C2745_RS05625 (C2745_05625) 1129036..1129890 + 855 WP_215383404.1 carboxylating nicotinate-nucleotide diphosphorylase -
C2745_RS09675 1129897..1130049 - 153 WP_251368298.1 hypothetical protein -
C2745_RS05635 (C2745_05635) 1130347..1132002 - 1656 WP_215383405.1 L-aspartate oxidase -
C2745_RS05640 (C2745_05640) 1132123..1132422 - 300 WP_215383406.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10929.65 Da        Isoelectric Point: 9.5229

>T172335 WP_215383401.1 NZ_CP061315:c1127512-1127231 [Polynucleobacter sp. AP-Kolm-20A-A1]
MRRIERTTQFKRDYKREAKGRYQAAISTILVEAVEFLVIDEALPARYFDHALTGQWSDFRDCHIKPDLILIYQKPNLDLL
RLVRLGSHSQLGL

Download         Length: 282 bp

>T172335 NZ_CP079735:c1130415-1129342 [Escherichia coli]
ATGACAATCAGGAGTTACAAAAACTTAAATCTGGTCAGGGCAAATATCGAGACTGAATCCAGACAATTCATTGAAAATAA
AAACTATTCAATCCAATCAATTGGTCCTATGCCAGGGTCAAGGGCTGGGCTTCGGGTCGTATTTACCAGACCAGGGGTTA
ACTTGGCAACTGTGGACATTTTTTATAACGGGGACGGTTCGACTACAATTCAATATCTCACTGGAGCCAATCGTTCTCTG
GGCCAAGAGTTAGCGGATCATCTTTTTGAAACCATCAATCCTGCTGAATTTGAGCAGGTAAATATGGTACTGCAAGGATT
TGTAGAGACAAGCGTTCTACCTGTACTTGAGCTATCAGCAGATGAATCGCATATAGAGTTCAGAGAACACTCTCGTAACG
CTCATACCGTAGTGTGGAAAATTATTTCCACCAGCTATCAGGACGAATTGACTGTGAGCCTGCATATCACAACAGGTAAG
CTCCAGATTCAGGGCCGACCGCTGTCATGTTACAGAGTTTTCACGTTTAACTTGGCAGCCCTGCTTGATTTACAGGGTTT
GGAGAAAGTGCTAATCCGCCAGGAGGATGGTAAAGCTAATATTGTTCAACAGGAGGTTGCCCGCACTTACTTGCAGACTG
TAATGGCCGATGCTTACCCGCATCTCCACGTGACTGCCGAAAAATTGCTCGTTTCAGGGCTATGTGTTAAACTCGCCGCC
CCTGATTTGCCTGACTACTGTATGTTACTTTATCCTGAACTACGCACCATTGAAGGTGTCTTAAAAAGTAAGATGAGTGG
GTTAGGCATGCCAGTACAGCAGCCGGCAGGTTTTGGAACTTACTTTGATAAACCTGCTGCTCATTACATTCTGAAACCGC
AATTTGCAGCTACTCTTAGACCGGAACAGATTAACATCATCAGCACAGCCTATACTTTTTTTAATGTGGAACGTCATTCT
CTGTTCCACATGGAAACTGTGGTCGATGCCAGCCGTATGATTTCTGATATGGCCCGGTTGATGGGTAAAGCCACTAGAGC
GTGGGGAATAATCAAGGACTTATATATTGTTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9623.34 Da        Isoelectric Point: 6.3497

>AT172335 WP_215383402.1 NZ_CP061315:c1127762-1127499 [Polynucleobacter sp. AP-Kolm-20A-A1]
MTANAVVRARIEEGIKKEASLVLEAMGLTVSDALRMMLIRVATEKSLPFEPLMPNAKTIAAMREARERQLMSFGSAKDLM
KDLNAED

Download         Length: 264 bp

>AT172335 NZ_CP079735:c1129349-1128978 [Escherichia coli]
TTGTTTGAAATCACCGGAATTAACGTCTCAGGGGCTCTAAAAGCTGTCGTTATGGCGACCGGCTTCGAGAACCCTTTGTC
CTCAGTTAATGAAATTGAGACGAAACTTTCTGCCCTACTGGGTAGTGAGACCACTGGTGAAATCCTTTTTGACCTCTTGT
GCGCTAACGGTCCAGAGTGGAACCGCTTCGTTACGCTGGAAATGAAATATGGCCGGATCATGCTGGATACGGCCAAAATT
ATTGATGAGCAGGACGTTCCGACACATATCCTGAGCAAACTGACTTTTACTTTACGTAATCATCCTGAGTACCTAGAAGC
CTCTGTTTTGTCTCCCGATGATGTACGCCAAGTCCTGTCAATGGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References