Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ParST/RES-TIGR02293 |
| Location | 260191..261161 | Replicon | chromosome |
| Accession | NZ_CP061314 | ||
| Organism | Polynucleobacter corsicus strain AP-Melu-1000-A1 | ||
Toxin (Protein)
| Gene name | ParT | Uniprot ID | - |
| Locus tag | C2747_RS01425 | Protein ID | WP_215331941.1 |
| Coordinates | 260688..261161 (+) | Length | 158 a.a. |
Antitoxin (Protein)
| Gene name | ParS | Uniprot ID | - |
| Locus tag | C2747_RS01420 | Protein ID | WP_215331940.1 |
| Coordinates | 260191..260691 (+) | Length | 167 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C2747_RS01390 (C2747_01390) | 255451..255999 | + | 549 | WP_251374784.1 | GspH/FimT family protein | - |
| C2747_RS01395 (C2747_01395) | 256048..257163 | + | 1116 | WP_215331935.1 | bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD | - |
| C2747_RS01400 (C2747_01400) | 257203..257817 | + | 615 | WP_215331936.1 | riboflavin synthase | - |
| C2747_RS01405 (C2747_01405) | 258018..258758 | - | 741 | WP_215331937.1 | 7-cyano-7-deazaguanine synthase QueC | - |
| C2747_RS01410 (C2747_01410) | 258785..259516 | - | 732 | WP_215331938.1 | tol-pal system protein YbgF | - |
| C2747_RS01415 (C2747_01415) | 259516..260016 | - | 501 | WP_215331939.1 | peptidoglycan-associated lipoprotein Pal | - |
| C2747_RS01420 (C2747_01420) | 260191..260691 | + | 501 | WP_215331940.1 | DUF2384 domain-containing protein | Antitoxin |
| C2747_RS01425 (C2747_01425) | 260688..261161 | + | 474 | WP_215331941.1 | RES family NAD+ phosphorylase | Toxin |
| C2747_RS01430 (C2747_01430) | 261173..262480 | - | 1308 | WP_251374785.1 | Tol-Pal system beta propeller repeat protein TolB | - |
| C2747_RS01435 (C2747_01435) | 262484..263299 | - | 816 | WP_215331942.1 | cell envelope integrity protein TolA | - |
| C2747_RS01440 (C2747_01440) | 263319..263738 | - | 420 | WP_215331943.1 | ExbD/TolR family protein | - |
| C2747_RS01445 (C2747_01445) | 263741..264397 | - | 657 | WP_215331944.1 | protein TolQ | - |
| C2747_RS01450 (C2747_01450) | 264474..265718 | + | 1245 | WP_215331945.1 | serine hydroxymethyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 158 a.a. Molecular weight: 17091.91 Da Isoelectric Point: 10.3023
>T172331 WP_215331941.1 NZ_CP061314:260688-261161 [Polynucleobacter corsicus]
MSVQAVWRIALDAPLFKADDLSGEGAKKSGGRWNKKGTSVLYTSESIALACLETMVHINAQGLPLTRYLVRIDIPVRVWN
LAKRLNAKTAGTGWDALPAGTASIEKGQKWLQSNTSALLLVPSVVIPQASNVLINPMHPDIKLIKAKKIEQFSYDPS
MSVQAVWRIALDAPLFKADDLSGEGAKKSGGRWNKKGTSVLYTSESIALACLETMVHINAQGLPLTRYLVRIDIPVRVWN
LAKRLNAKTAGTGWDALPAGTASIEKGQKWLQSNTSALLLVPSVVIPQASNVLINPMHPDIKLIKAKKIEQFSYDPS
Download Length: 474 bp
>T172331 NZ_CP079735:719141-719437 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA
Antitoxin
Download Length: 167 a.a. Molecular weight: 18033.09 Da Isoelectric Point: 9.2888
>AT172331 WP_215331940.1 NZ_CP061314:260191-260691 [Polynucleobacter corsicus]
MPSVIPKKAATKVLLKSPPVITQLDLSFATIYKVEPIDRIKLIRDGVPARYINVISDSMGITKETLFKFLNLPKSTIDKK
SVANQMLPIEQGERLIGMAKLVGQVESMITESGNPDGFDAAKWVASWLEKPSPALGGEKPSAYLDTVSGQEMISDLLAKI
QTGAYA
MPSVIPKKAATKVLLKSPPVITQLDLSFATIYKVEPIDRIKLIRDGVPARYINVISDSMGITKETLFKFLNLPKSTIDKK
SVANQMLPIEQGERLIGMAKLVGQVESMITESGNPDGFDAAKWVASWLEKPSPALGGEKPSAYLDTVSGQEMISDLLAKI
QTGAYA
Download Length: 501 bp
>AT172331 NZ_CP079735:719439-719834 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|