Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 325615..326095 Replicon chromosome
Accession NZ_CP061298
Organism Polynucleobacter paludilacus strain MWH-Mekk-C3

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag AOC06_RS01805 Protein ID WP_215380761.1
Coordinates 325826..326095 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag AOC06_RS01800 Protein ID WP_215380759.1
Coordinates 325615..325842 (+) Length 76 a.a.

Genomic Context

AOC06_RS01775AOC06_RS01785AOC06_RS01790AOC06_RS01795AOC06_RS01800AOC06_RS01805AOC06_RS01810AOC06_RS01815AOC06_RS01820AOC06_RS01835AOC06_RS01780AOC06_RS01825AOC06_RS01830AOC06_RS01840
Location: 321551..322543 (993 bp)
Type: Others
Protein ID: WP_215380745.1
Location: 323688..323930 (243 bp)
Type: Others
Protein ID: WP_215380751.1
Location: 323927..324376 (450 bp)
Type: Others
Protein ID: WP_215380754.1
Location: 324486..325415 (930 bp)
Type: Others
Protein ID: WP_215380757.1
Location: 325615..325842 (228 bp)
Type: Antitoxin
Protein ID: WP_215380759.1
Location: 325826..326095 (270 bp)
Type: Toxin
Protein ID: WP_215380761.1
Location: 326371..326712 (342 bp)
Type: Others
Protein ID: WP_206603336.1
Location: 326709..327083 (375 bp)
Type: Others
Protein ID: WP_215380763.1
Location: 327147..327524 (378 bp)
Type: Others
Protein ID: WP_112294899.1
Location: 329810..330172 (363 bp)
Type: Others
Protein ID: WP_215284471.1
Location: 322587..323606 (1020 bp)
Type: Others
Protein ID: WP_215380748.1
Location: 327578..328648 (1071 bp)
Type: Others
Protein ID: WP_215380765.1
Location: 328720..329739 (1020 bp)
Type: Others
Protein ID: WP_112294897.1
Location: 330095..330907 (813 bp)
Type: Others
Protein ID: WP_215284657.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AOC06_RS01775 (AOC06_01775)321551..322543+993WP_215380745.1NAD-dependent epimerase/dehydratase family protein-
AOC06_RS01780 (AOC06_01780)322587..323606-1020WP_215380748.1tyrosine-type recombinase/integrase-
AOC06_RS01785 (AOC06_01785)323688..323930+243WP_215380751.1XRE family transcriptional regulator-
AOC06_RS01790 (AOC06_01790)323927..324376+450WP_215380754.1hypothetical protein-
AOC06_RS01795 (AOC06_01795)324486..325415+930WP_215380757.1hypothetical protein-
AOC06_RS01800 (AOC06_01800)325615..325842+228WP_215380759.1ribbon-helix-helix domain-containing proteinAntitoxin
AOC06_RS01805 (AOC06_01805)325826..326095+270WP_215380761.1type II toxin-antitoxin system RelE/ParE family toxinToxin
AOC06_RS01810 (AOC06_01810)326371..326712+342WP_206603336.1DUF6516 family protein-
AOC06_RS01815 (AOC06_01815)326709..327083+375WP_215380763.1MarR family transcriptional regulator-
AOC06_RS01820 (AOC06_01820)327147..327524+378WP_112294899.1hypothetical protein-
AOC06_RS01825 (AOC06_01825)327578..328648-1071WP_215380765.1glycosyltransferase-
AOC06_RS01830 (AOC06_01830)328720..329739-1020WP_112294897.1ionic transporter y4hA-
AOC06_RS01835 (AOC06_01835)329810..330172+363WP_215284471.1CbiX/SirB N-terminal domain-containing protein-
AOC06_RS01840 (AOC06_01840)330095..330907-813WP_215284657.1uroporphyrinogen-III C-methyltransferase-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Predicted DNA-binding protein, ribbon-helix-helix domain

(3-35)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10445.28 Da        Isoelectric Point: 10.1284

>T172314 WP_215380761.1 NZ_CP061298:325826-326095 [Polynucleobacter paludilacus]
MAWIIKYTESSSKQLKKLDKQTALRVLDYMDERVAVLNDPRSLGKNLKGPKIGEYWRYRVGDIRVICNIVDGQMMVLVIE
IGNRREVYR

Download         Length: 270 bp

>T172314 NZ_CP079725:845182-845592 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGACGGATCCATGCCCGTCGCGGGGAAATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8577.69 Da        Isoelectric Point: 4.4857

>AT172314 WP_215380759.1 NZ_CP061298:325615-325842 [Polynucleobacter paludilacus]
MAVSIRLDPEIEQRLDQLAAQTGRAKSYYLRELIEGGLDDLEDFYLADAVMERVRRGSEKLLDATQVRKDLGLDH

Download         Length: 228 bp

>AT172314 NZ_CP079725:844935-845201 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References