172310

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParST/RES-TIGR02293
Location 258588..259573 Replicon chromosome
Accession NZ_CP061297
Organism Polynucleobacter asymbioticus strain MWH-MoIso1

Toxin (Protein)


Gene name ParT Uniprot ID -
Locus tag AOC19_RS01395 Protein ID WP_215376898.1
Coordinates 259085..259573 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name ParS Uniprot ID -
Locus tag AOC19_RS01390 Protein ID WP_215376895.1
Coordinates 258588..259088 (+) Length 167 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOC19_RS01355 (AOC19_01355) 253735..254037 + 303 WP_215376878.1 hypothetical protein -
AOC19_RS01360 (AOC19_01360) 254030..254578 + 549 WP_251368051.1 GspH/FimT family pseudopilin -
AOC19_RS01365 (AOC19_01365) 254626..255741 + 1116 WP_215376881.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
AOC19_RS01370 (AOC19_01370) 255784..256401 + 618 WP_215376884.1 riboflavin synthase -
AOC19_RS01375 (AOC19_01375) 256412..257152 - 741 WP_215376887.1 7-cyano-7-deazaguanine synthase QueC -
AOC19_RS01380 (AOC19_01380) 257182..257913 - 732 WP_215376890.1 tol-pal system protein YbgF -
AOC19_RS01385 (AOC19_01385) 257913..258413 - 501 WP_215376892.1 peptidoglycan-associated lipoprotein Pal -
AOC19_RS01390 (AOC19_01390) 258588..259088 + 501 WP_215376895.1 DUF2384 domain-containing protein Antitoxin
AOC19_RS01395 (AOC19_01395) 259085..259573 + 489 WP_215376898.1 RES family NAD+ phosphorylase Toxin
AOC19_RS01400 (AOC19_01400) 259570..260823 - 1254 WP_215377978.1 Tol-Pal system beta propeller repeat protein TolB -
AOC19_RS01405 (AOC19_01405) 260881..261687 - 807 WP_215376902.1 cell envelope integrity protein TolA -
AOC19_RS01410 (AOC19_01410) 261707..262126 - 420 WP_114651896.1 ExbD/TolR family protein -
AOC19_RS01415 (AOC19_01415) 262129..262785 - 657 WP_215376905.1 protein TolQ -
AOC19_RS01420 (AOC19_01420) 262862..264106 + 1245 WP_215376908.1 serine hydroxymethyltransferase -
AOC19_RS01425 (AOC19_01425) 264118..264564 + 447 WP_215376911.1 transcriptional regulator NrdR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(6-153)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(119-163)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17677.60 Da        Isoelectric Point: 10.3015

>T172310 WP_215376898.1 NZ_CP061297:259085-259573 [Polynucleobacter asymbioticus]
MSVQEVWRIALDAPLFKADDLSGEGAKKSGGRWNKKGTPVLYTSESIALACLETLVHINAQGLPLTRYLVRIDIPTRVWN
LAKRLNPKTAGAGWDALPAGAASIEKGQKWLQSNASALLFVPSVVIPQASNVLINPMHPDIKLIKAKKIEQFSYDPRLVG
QP

Download         Length: 489 bp

>T172310 NZ_CP079719:c1277608-1276862 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCGCTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCCGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCGGACGTTCAGTCCCGTCTTAA
CCGTAAAGATGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin


Download         Length: 167 a.a.        Molecular weight: 18224.22 Da        Isoelectric Point: 9.8764

>AT172310 WP_215376895.1 NZ_CP061297:258588-259088 [Polynucleobacter asymbioticus]
MPSVIHKKATTRVLRKSSLEITQQDLSFATIYRVEPMDRIKLIRGGIPARYINVISDSMGITKETLFKFLNLPKSTIDKK
SVANQMLPIEQGERLIGMAKLVGQIESIIAESGNPDGFNAAKWMASWLEKPSPALGGEKPSAYLDTVSGQEMISDLLAKI
QTGAYA

Download         Length: 501 bp

>AT172310 NZ_CP079719:c1276861-1276691 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References