Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 588719..589308 Replicon chromosome
Accession NZ_CP061291
Organism Polynucleobacter sp. TSB-Sco08W16

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FD961_RS03095 Protein ID WP_215394061.1
Coordinates 588719..589102 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FD961_RS03100 Protein ID WP_215394062.1
Coordinates 589105..589308 (-) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD961_RS03080 (FD961_03080) 584274..585392 + 1119 WP_215394059.1 alanine dehydrogenase -
FD961_RS03085 (FD961_03085) 585474..586049 + 576 WP_071464946.1 TMEM165/GDT1 family protein -
FD961_RS03090 (FD961_03090) 586095..588704 + 2610 WP_215394060.1 aminopeptidase N -
FD961_RS03095 (FD961_03095) 588719..589102 - 384 WP_215394061.1 PIN domain-containing protein Toxin
FD961_RS03100 (FD961_03100) 589105..589308 - 204 WP_215394062.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FD961_RS03105 (FD961_03105) 589504..590484 + 981 WP_215394332.1 class 1 fructose-bisphosphatase -
FD961_RS03110 (FD961_03110) 590580..593150 - 2571 WP_215394063.1 cyanophycin synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14089.35 Da        Isoelectric Point: 6.0558

>T172292 WP_215394061.1 NZ_CP061291:c589102-588719 [Polynucleobacter sp. TSB-Sco08W16]
MPMILADTSVWVSHFRKSNASFASLLANDQILCHPLILIELACGSLPSPRSRTLNYLKMLRQATVATTEETMNFIETHKL
YDSGCGAIDISLVASTLLSENALIWTLDKQLELLAIQLGVSYNQQLH

Download         Length: 384 bp

>T172292 NZ_CP079715:2413232-2413327 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7378.53 Da        Isoelectric Point: 10.3534

>AT172292 WP_215394062.1 NZ_CP061291:c589308-589105 [Polynucleobacter sp. TSB-Sco08W16]
MRTTVTIDDDLYQTGLDLADPGMDKADLFREAMTVFVRVQSAKRLAALGGKVPQMKAIPRRKNNGGQ

Download         Length: 204 bp

>AT172292 NZ_CP079715:c2413414-2413355 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References