Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4286507..4286775 Replicon chromosome
Accession NZ_CP061206
Organism Escherichia coli strain DA61218

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4286635..4286737 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4286507..4286775 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICI53_RS19860 4283059..4283721 - 663 WP_000944256.1 exodeoxyribonuclease X -
ICI53_RS19865 4283745..4284401 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
ICI53_RS19870 4284504..4284734 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ICI53_RS19875 4284873..4285247 + 375 WP_000168747.1 CopC domain-containing protein YobA -
ICI53_RS19880 4285251..4286123 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
ICI53_RS19885 4286136..4286477 + 342 WP_000984819.1 YebY family protein -
- 4286507..4286775 - 269 - - Antitoxin
- 4286635..4286737 + 103 - - Toxin
ICI53_RS19890 4286872..4287528 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
ICI53_RS19895 4287529..4287720 - 192 WP_001317886.1 YebW family protein -
ICI53_RS19900 4287825..4288061 - 237 WP_001295499.1 DUF1480 family protein -
ICI53_RS19905 4288179..4289618 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T172246 NZ_CP061206:4286635-4286737 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT172246 NZ_CP061206:c4286775-4286507 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References