Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3883443..3884916 Replicon chromosome
Accession NZ_CP061205
Organism Kordiimonas pumila strain N18

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag ICL80_RS17315 Protein ID WP_194213974.1
Coordinates 3884053..3884916 (+) Length 288 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag ICL80_RS17310 Protein ID WP_194213973.1
Coordinates 3883443..3884060 (+) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICL80_RS17290 3880976..3881185 - 210 WP_194213970.1 helix-turn-helix transcriptional regulator -
ICL80_RS17295 3881134..3882345 - 1212 WP_194213971.1 type II toxin-antitoxin system HipA family toxin -
ICL80_RS17300 3882625..3882837 + 213 WP_194213972.1 antitoxin MazE family protein -
ICL80_RS17305 3882834..3883065 + 232 Protein_3410 type II toxin-antitoxin system PemK/MazF family toxin -
ICL80_RS17310 3883443..3884060 + 618 WP_194213973.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
ICL80_RS17315 3884053..3884916 + 864 WP_194213974.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
ICL80_RS17320 3885020..3885316 + 297 WP_194213975.1 hypothetical protein -
ICL80_RS17325 3885321..3888509 - 3189 WP_194213976.1 conjugal transfer protein TraG N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3847752..3938539 90787


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-257)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(9-93)


Sequences

Toxin        


Download         Length: 288 a.a.        Molecular weight: 32224.68 Da        Isoelectric Point: 4.9385

>T172225 WP_194213974.1 NZ_CP061205:3884053-3884916 [Kordiimonas pumila]
MVKVSPVSIKQRLHNHARSSGRVYNTVLIAYGLQRLIYRLSVSKHANDYILKGGMLVTQWTLDSVRPTKDLDFLGFGDSD
ADHLIDVFSEVMELDGDDGLNFDTATLAATPIRDTQDYGGIRLKTTAYLDKTKIPITIDVGFGDAIVDPDYRIDYPSLLD
MPPATLRAYPPESVIAEKFHAVVALGLINSRMKDYYDLWSIPQALALNEDMLDKAIAETFKRRGHAIPTTCPPGFSDMFA
EDAEKKRQWAAYAESVNLENVSLQRVTEEIWDYLAPACARICKREET

Download         Length: 864 bp

>T172225 NZ_CP079668:c2817766-2816444 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCACCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACTCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22670.34 Da        Isoelectric Point: 10.0226

>AT172225 WP_194213973.1 NZ_CP061205:3883443-3884060 [Kordiimonas pumila]
MTELETQKDHLISILQDQTVVRARDLRSEGIAASTVARAVKTGDIIKIDRGLYQLQNGQVHEEQALAEVSKRVPNGTICM
MSALAFHGVTDQIPAKTWVAIGPKDWAPKITYPPIRFVRFQKKYLHYGIEFHMIGGVKVPVYSISKTLADAFRNPKLLDR
SVAIEAMKNALEARKVTPSGIAEAASVCGAWKKIRPYLEAITSNG

Download         Length: 618 bp

>AT172225 NZ_CP079668:c2818032-2817766 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGATGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References