Detailed information of TA system TA172224

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 330439..330795
• Replicon: chromosome
• Accession: NZ_CP061204
• Organism: Stenotrophomonas sp. 169

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: -
• Locus tag: ICJ04_RS01335
• Protein ID: WP_188325780.1
• Coordinates: 330658..330795 (+)
• Length: 46 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: ICJ04_RS01330
• Protein ID: WP_188325779.1
• Coordinates: 330439..330591 (+)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICJ04_RS01295	325612..326430	+	819	WP_188325774.1	SPOR domain-containing protein	-
ICJ04_RS01305	326643..327182	-	540	WP_188325775.1	GTPase	-
ICJ04_RS01310	327179..328138	-	960	WP_188325776.1	hypothetical protein	-
ICJ04_RS01315	328212..328571	-	360	WP_188327162.1	roadblock/LC7 domain-containing protein	-
ICJ04_RS01320	328653..329105	-	453	WP_188325777.1	roadblock/LC7 domain-containing protein	-
ICJ04_RS01325	329378..330295	+	918	WP_188325778.1	arginase	-
ICJ04_RS01330	330439..330591	+	153	WP_188325779.1	entericidin A/B family lipoprotein	Antitoxin
ICJ04_RS01335	330658..330795	+	138	WP_188325780.1	entericidin A/B family lipoprotein	Toxin
ICJ04_RS01340	330992..331213	+	222	WP_188325781.1	CsbD family protein	-
ICJ04_RS01345	331277..332089	-	813	WP_188325782.1	hypothetical protein	-
ICJ04_RS01350	332202..333491	+	1290	WP_188325783.1	tryptophan--tRNA ligase	-
ICJ04_RS01355	333559..333858	+	300	WP_188325784.1	hypothetical protein	-
ICJ04_RS01360	333958..334890	+	933	WP_188325785.1	MBL fold metallo-hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 46 a.a.
• Molecular weight: 4625.48 Da
• Isoelectric Point: 9.3487

>T172224 WP_188325780.1 NZ_CP061204:330658-330795 [Stenotrophomonas sp. 169]
MKRAIALMLLSMFSVAMLAGCNTVAGAGKDVQGAGEKVEDAARKN

Nucleotide

• Length: 138 bp

>T172224 NZ_CP079668:2068104-2068206 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5086.88 Da
• Isoelectric Point: 7.6402

>AT172224 WP_188325779.1 NZ_CP061204:330439-330591 [Stenotrophomonas sp. 169]
MKRIISVLLFALCTAGSLTACNTVAGAGKDMQSAGDAVHDTAQDCKNGKC

Nucleotide

• Length: 153 bp

>AT172224 NZ_CP079668:c2068213-2068068 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT