Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 3445009..3445616 Replicon chromosome
Accession NZ_CP061202
Organism Rhodobacter capsulatus strain A12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H9N28_RS16465 Protein ID WP_055211120.1
Coordinates 3445009..3445275 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H9N28_RS16470 Protein ID WP_055210839.1
Coordinates 3445272..3445616 (+) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9N28_RS16445 3442349..3442897 - 549 WP_081024475.1 PIN domain-containing protein -
H9N28_RS16450 3442899..3443252 - 354 WP_081024476.1 STAS-like domain-containing protein -
H9N28_RS16455 3443254..3444213 - 960 WP_146707256.1 ATP-binding protein -
H9N28_RS16460 3444588..3444824 - 237 WP_188323864.1 hypothetical protein -
H9N28_RS16465 3445009..3445275 + 267 WP_055211120.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H9N28_RS16470 3445272..3445616 + 345 WP_055210839.1 helix-turn-helix transcriptional regulator Antitoxin
H9N28_RS16475 3445642..3446139 + 498 WP_146707255.1 hypothetical protein -
H9N28_RS16480 3446560..3447117 + 558 WP_146707254.1 hypothetical protein -
H9N28_RS16485 3447990..3448490 + 501 WP_146707253.1 hypothetical protein -
H9N28_RS16490 3448633..3449169 + 537 WP_055210845.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3439592..3457779 18187


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-79)

Antitoxin

Cro/C1-type helix-turn-helix domain

(59-112)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 9619.11 Da        Isoelectric Point: 10.6598

>T172223 WP_055211120.1 NZ_CP061202:3445009-3445275 [Rhodobacter capsulatus]
MKQISYTKAAIKALRRMPSNTAAPIRAEIEAYAQDPSAQANNVKPLKGREGIRLRVGDWRVIMDDQGNVLAVLDIGPRGG
VYDGKGLR

Download         Length: 267 bp

>T172223 NZ_CP079668:818768-819178 [Klebsiella pneumoniae subsp. pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGAAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12483.03 Da        Isoelectric Point: 4.6493

>AT172223 WP_055210839.1 NZ_CP061202:3445272-3445616 [Rhodobacter capsulatus]
MNEMVTIPREEYDRLRAAAEDLADLQSYDRARARLAAGEDELIPADYANRLLNGESALRVFRDLRGLTQAALAEKSGVKR
VTVAEIETGRKHGSIATLRALADALGVSLDDLTE

Download         Length: 345 bp

>AT172223 NZ_CP079668:818521-818787 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References