Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 6997..7528 Replicon plasmid ps12201A.p2
Accession NZ_CP061192
Organism Piscirickettsia salmonis strain Ps12201A

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ICC15_RS16945 Protein ID WP_016210662.1
Coordinates 6997..7284 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ICC15_RS16950 Protein ID WP_016210670.1
Coordinates 7274..7528 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICC15_RS16910 2001..2324 + 324 WP_032126913.1 hypothetical protein -
ICC15_RS16915 2381..2647 + 267 WP_016211142.1 DUF4035 domain-containing protein -
ICC15_RS16920 2651..4729 + 2079 WP_032126912.1 hypothetical protein -
ICC15_RS16925 4722..5061 + 340 Protein_8 phage tail protein -
ICC15_RS16930 5058..5729 + 672 WP_016210666.1 phage minor tail protein L -
ICC15_RS16935 5680..6445 + 766 Protein_10 C40 family peptidase -
ICC15_RS16940 6435..6990 + 556 Protein_11 tail assembly protein -
ICC15_RS16945 6997..7284 - 288 WP_016210662.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ICC15_RS16950 7274..7528 - 255 WP_016210670.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ICC15_RS16955 7622..10909 + 3288 WP_016210653.1 host specificity protein J -
ICC15_RS16960 10909..12066 + 1158 WP_188322421.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..89447 89447


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-55)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11064.15 Da        Isoelectric Point: 10.7358

>T172218 WP_016210662.1 NZ_CP061192:c7284-6997 [Piscirickettsia salmonis]
MTYKLQFHKEAYKEWKKLNPTTQQQFQKVLKKRLINPHIPSAVCGGDLKGCYKIKLRALGYRLIYTVKEDKVVVQVLAIG
SRNRLEAYRLAASRL

Download         Length: 288 bp

>T172218 NZ_CP079655:c5415948-5415565 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9450.69 Da        Isoelectric Point: 4.0808

>AT172218 WP_016210670.1 NZ_CP061192:c7528-7274 [Piscirickettsia salmonis]
MKQLYAQQSVTITELRKSPTSVINEANGEPVVILNHNAPAAYMVPPELFEAMLDSYEDRQLEGIVKKRLNSPDCDFIDVD
VDDL

Download         Length: 255 bp

>AT172218 NZ_CP079655:c5416190-5415948 [Klebsiella pneumoniae subsp. pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References