Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 1149211..1149865 Replicon chromosome
Accession NZ_CP061170
Organism Microbacterium sp. HY82

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HCR84_RS05540 Protein ID WP_166984337.1
Coordinates 1149211..1149603 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HCR84_RS05545 Protein ID WP_166984336.1
Coordinates 1149605..1149865 (-) Length 87 a.a.

Genomic Context

HCR84_RS05520HCR84_RS05525HCR84_RS05530HCR84_RS05535HCR84_RS05550HCR84_RS05555HCR84_RS05560HCR84_RS05540HCR84_RS05545
Location: 1145160..1145957 (798 bp)
Type: Others
Protein ID: WP_166984340.1
Location: 1145999..1146754 (756 bp)
Type: Others
Protein ID: WP_166984339.1
Location: 1146823..1147563 (741 bp)
Type: Others
Protein ID: WP_166984357.1
Location: 1147620..1149167 (1548 bp)
Type: Others
Protein ID: WP_166984338.1
Location: 1150000..1150980 (981 bp)
Type: Others
Protein ID: WP_166984335.1
Location: 1150977..1151786 (810 bp)
Type: Others
Protein ID: WP_166984334.1
Location: 1151983..1153698 (1716 bp)
Type: Others
Protein ID: WP_166984333.1
Location: 1149211..1149603 (393 bp)
Type: Toxin
Protein ID: WP_166984337.1
Location: 1149605..1149865 (261 bp)
Type: Antitoxin
Protein ID: WP_166984336.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HCR84_RS055201145160..1145957+798WP_166984340.1fructosamine kinase family protein-
HCR84_RS055251145999..1146754+756WP_166984339.1SDR family oxidoreductase-
HCR84_RS055301146823..1147563+741WP_166984357.1sulfite exporter TauE/SafE family protein-
HCR84_RS055351147620..1149167+1548WP_166984338.1DASS family sodium-coupled anion symporter-
HCR84_RS055401149211..1149603-393WP_166984337.1type II toxin-antitoxin system VapC family toxinToxin
HCR84_RS055451149605..1149865-261WP_166984336.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
HCR84_RS055501150000..1150980+981WP_166984335.1ATP-binding cassette domain-containing protein-
HCR84_RS055551150977..1151786+810WP_166984334.1ABC transporter permease-
HCR84_RS055601151983..1153698+1716WP_166984333.1sodium:proton antiporter-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-50)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 13745.61 Da        Isoelectric Point: 4.1746

>T172161 WP_166984337.1 NZ_CP061170:c1149603-1149211 [Microbacterium sp. HY82]
VAYYLDTSALVKLVVAEAESAALHEWLTSCESELVTCDLARTELMRAVRPVSPDRAVRAREVLESVFSLSLSTATYDAAA
RLQPPELCSLDAVHLAAALELGADLEGIIVYDGHLADAAGSYGITTIAPA

Download         Length: 393 bp

>T172161 NZ_CP079629:c5410059-5409676 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9275.57 Da        Isoelectric Point: 11.5079

>AT172161 WP_166984336.1 NZ_CP061170:c1149865-1149605 [Microbacterium sp. HY82]
MDDVGIRALKQNASAVVASVAEGRSVTITDRGRPVAQLSPLVSGELNRLLVSGRLRAPRRSLRDLSVPAPGELTPALRGQ
RDDERY

Download         Length: 261 bp

>AT172161 NZ_CP079629:c5410301-5410059 [Klebsiella pneumoniae subsp. pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References