Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 944716..945380 Replicon chromosome
Accession NZ_CP061170
Organism Microbacterium sp. HY82

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HCR84_RS04580 Protein ID WP_166984052.1
Coordinates 944716..945138 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HCR84_RS04585 Protein ID WP_166984051.1
Coordinates 945135..945380 (-) Length 82 a.a.

Genomic Context

HCR84_RS04550HCR84_RS04565HCR84_RS04570HCR84_RS04575HCR84_RS04590HCR84_RS04620HCR84_RS04545HCR84_RS04555HCR84_RS04560HCR84_RS04580HCR84_RS04585HCR84_RS04595HCR84_RS04600HCR84_RS04605HCR84_RS04610HCR84_RS04615
Location: 941284..941859 (576 bp)
Type: Others
Protein ID: WP_166984058.1
Location: 943249..943941 (693 bp)
Type: Others
Protein ID: WP_166984055.1
Location: 944085..944231 (147 bp)
Type: Others
Protein ID: WP_166984054.1
Location: 944271..944723 (453 bp)
Type: Others
Protein ID: WP_166984053.1
Location: 945561..945674 (114 bp)
Type: Others
Protein ID: Protein_904
Location: 949027..950277 (1251 bp)
Type: Others
Protein ID: WP_166984046.1
Location: 940124..941158 (1035 bp)
Type: Others
Protein ID: WP_166984059.1
Location: 941856..942491 (636 bp)
Type: Others
Protein ID: WP_166984057.1
Location: 942508..943152 (645 bp)
Type: Others
Protein ID: WP_166984056.1
Location: 944716..945138 (423 bp)
Type: Toxin
Protein ID: WP_166984052.1
Location: 945135..945380 (246 bp)
Type: Antitoxin
Protein ID: WP_166984051.1
Location: 945702..946133 (432 bp)
Type: Others
Protein ID: WP_166984050.1
Location: 946130..946360 (231 bp)
Type: Others
Protein ID: WP_166984049.1
Location: 946463..947701 (1239 bp)
Type: Others
Protein ID: WP_166984048.1
Location: 947644..948504 (861 bp)
Type: Others
Protein ID: WP_166984165.1
Location: 948583..948957 (375 bp)
Type: Others
Protein ID: WP_166984047.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HCR84_RS04545940124..941158-1035WP_166984059.1saccharopine dehydrogenase NADP-binding domain-containing protein-
HCR84_RS04550941284..941859+576WP_166984058.1TetR/AcrR family transcriptional regulator-
HCR84_RS04555941856..942491-636WP_166984057.1maleylpyruvate isomerase family mycothiol-dependent enzyme-
HCR84_RS04560942508..943152-645WP_166984056.1maleylpyruvate isomerase family mycothiol-dependent enzyme-
HCR84_RS04565943249..943941+693WP_166984055.1helix-turn-helix transcriptional regulator-
HCR84_RS04570944085..944231+147WP_166984054.1hypothetical protein-
HCR84_RS04575944271..944723+453WP_166984053.1virulence RhuM family protein-
HCR84_RS04580944716..945138-423WP_166984052.1VapC toxin family PIN domain ribonucleaseToxin
HCR84_RS04585945135..945380-246WP_166984051.1hypothetical proteinAntitoxin
HCR84_RS04590945561..945674+114Protein_904cation:dicarboxylase symporter family transporter-
HCR84_RS04595945702..946133-432WP_166984050.1PIN domain-containing protein-
HCR84_RS04600946130..946360-231WP_166984049.1CopG family transcriptional regulator-
HCR84_RS04605946463..947701-1239WP_166984048.1aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme-
HCR84_RS04610947644..948504-861WP_166984165.1formyltetrahydrofolate deformylase-
HCR84_RS04615948583..948957-375WP_166984047.1MerR family transcriptional regulator-
HCR84_RS04620949027..950277+1251WP_166984046.1MFS transporter-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-136)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15974.07 Da        Isoelectric Point: 5.5688

>T172160 WP_166984052.1 NZ_CP061170:c945138-944716 [Microbacterium sp. HY82]
VKLLDVGVWLAAAWGRHIAHPTVQSWFDQQDSELVFCRVTEMGFLRLLSNPSIMREDTLTRADSWSVLDRLRADERVIHL
EEPTNLESVWRTLSARGDTSHKLWTDDYLAAFAQARGLSVVTLDRAFAGRHQSLEVELLS

Download         Length: 423 bp

>T172160 NZ_CP079629:c5096634-5095717 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCATCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGCGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8602.77 Da        Isoelectric Point: 7.0097

>AT172160 WP_166984051.1 NZ_CP061170:c945380-945135 [Microbacterium sp. HY82]
MRTTVDLPDDLLRALKVRAAQRGETLKVVLTRAISREIAGSTNTHTRVTLPLVAAGATPTVNVTSDDIAAALASDDEQYA
K

Download         Length: 246 bp

>AT172160 NZ_CP079629:c5097398-5096640 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGGCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References