Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 156214..156863 Replicon chromosome
Accession NZ_CP061169
Organism Microbacterium sp. HY60

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HCR76_RS00810 Protein ID WP_166985816.1
Coordinates 156474..156863 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HCR76_RS00805 Protein ID WP_166985818.1
Coordinates 156214..156477 (+) Length 88 a.a.

Genomic Context

HCR76_RS00790HCR76_RS00805HCR76_RS00810HCR76_RS00835HCR76_RS00780HCR76_RS00785HCR76_RS00795HCR76_RS00800HCR76_RS00815HCR76_RS00820HCR76_RS00825HCR76_RS00830
Location: 153666..154061 (396 bp)
Type: Others
Protein ID: WP_166985826.1
Location: 156214..156477 (264 bp)
Type: Antitoxin
Protein ID: WP_166985818.1
Location: 156474..156863 (390 bp)
Type: Toxin
Protein ID: WP_166985816.1
Location: 160703..161395 (693 bp)
Type: Others
Protein ID: WP_166985804.1
Location: 151587..152543 (957 bp)
Type: Others
Protein ID: WP_166985831.1
Location: 152635..153564 (930 bp)
Type: Others
Protein ID: WP_166985828.1
Location: 154077..155381 (1305 bp)
Type: Others
Protein ID: WP_166985823.1
Location: 155436..156137 (702 bp)
Type: Others
Protein ID: WP_166985821.1
Location: 156875..157459 (585 bp)
Type: Others
Protein ID: WP_166985814.1
Location: 157462..158157 (696 bp)
Type: Others
Protein ID: WP_166985812.1
Location: 158258..159112 (855 bp)
Type: Others
Protein ID: WP_166985810.1
Location: 159141..160553 (1413 bp)
Type: Others
Protein ID: WP_166985807.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HCR76_RS00780151587..152543-957WP_166985831.1thioredoxin domain-containing protein-
HCR76_RS00785152635..153564-930WP_166985828.1WYL domain-containing protein-
HCR76_RS00790153666..154061+396WP_166985826.1VOC family protein-
HCR76_RS00795154077..155381-1305WP_166985823.1hypothetical protein-
HCR76_RS00800155436..156137-702WP_166985821.1HAD hydrolase-like protein-
HCR76_RS00805156214..156477+264WP_166985818.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
HCR76_RS00810156474..156863+390WP_166985816.1type II toxin-antitoxin system VapC family toxinToxin
HCR76_RS00815156875..157459-585WP_166985814.1hypothetical protein-
HCR76_RS00820157462..158157-696WP_166985812.1endonuclease NucS-
HCR76_RS00825158258..159112-855WP_166985810.1NmrA family NAD(P)-binding protein-
HCR76_RS00830159141..160553-1413WP_166985807.1MFS transporter-
HCR76_RS00835160703..161395+693WP_166985804.1TetR/AcrR family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-115)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-50)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13686.58 Da        Isoelectric Point: 5.6263

>T172157 WP_166985816.1 NZ_CP061169:156474-156863 [Microbacterium sp. HY60]
VIYIDTSAVVKTLVSERGSSSVRRLFATSERLVSSRLLAVELNTAAQRRGLPAVHVDETLSRVNLVSVDDDVLDGAIRLQ
SGLRGLDALHLATAILIGDELTVFLAFDPELNAAARRSGLALHPASADG

Download         Length: 390 bp

>T172157 NZ_CP079629:4223300-4223518 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9422.56 Da        Isoelectric Point: 6.3283

>AT172157 WP_166985818.1 NZ_CP061169:156214-156477 [Microbacterium sp. HY60]
MGSVTRTELNQQTARVLARVAAGERVTITDRGRPIAELTPARESGWDALIAAGKVRTATRSGSLTFEPIDLDVSSSDIID
DIRRERG

Download         Length: 264 bp

>AT172157 NZ_CP079629:4222899-4223273 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References