Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-PHD
Location 94838..95502 Replicon chromosome
Accession NZ_CP061169
Organism Microbacterium sp. HY60

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HCR76_RS00505 Protein ID WP_166985937.1
Coordinates 94838..95242 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HCR76_RS00510 Protein ID WP_166985934.1
Coordinates 95242..95502 (-) Length 87 a.a.

Genomic Context

HCR76_RS00485HCR76_RS00490HCR76_RS00495HCR76_RS00500HCR76_RS00515HCR76_RS00505HCR76_RS00510HCR76_RS00520
Location: 90109..90927 (819 bp)
Type: Others
Protein ID: WP_198248106.1
Location: 90987..92024 (1038 bp)
Type: Others
Protein ID: WP_166985945.1
Location: 92031..94139 (2109 bp)
Type: Others
Protein ID: WP_166985942.1
Location: 94192..94587 (396 bp)
Type: Others
Protein ID: WP_166985939.1
Location: 95763..99308 (3546 bp)
Type: Others
Protein ID: WP_166985932.1
Location: 94838..95242 (405 bp)
Type: Toxin
Protein ID: WP_166985937.1
Location: 95242..95502 (261 bp)
Type: Antitoxin
Protein ID: WP_166985934.1
Location: 99331..99906 (576 bp)
Type: Others
Protein ID: WP_166985929.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HCR76_RS0048590109..90927+819WP_198248106.1ABC transporter ATP-binding protein-
HCR76_RS0049090987..92024+1038WP_166985945.1iron-siderophore ABC transporter substrate-binding protein-
HCR76_RS0049592031..94139+2109WP_166985942.1iron ABC transporter permease-
HCR76_RS0050094192..94587+396WP_166985939.1hypothetical protein-
HCR76_RS0050594838..95242-405WP_166985937.1type II toxin-antitoxin system VapC family toxinToxin
HCR76_RS0051095242..95502-261WP_166985934.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
HCR76_RS0051595763..99308+3546WP_166985932.1proline dehydrogenase family protein-
HCR76_RS0052099331..99906-576WP_166985929.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-121)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-46)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14364.46 Da        Isoelectric Point: 4.4482

>T172156 WP_166985937.1 NZ_CP061169:c95242-94838 [Microbacterium sp. HY60]
MRPAAKGLLDTSVFIALESGRPMNAEMLPDQSVICPVTIAELQAGVLSIADVDVRARRLSTLESTMDIELLAIDAEVAAH
WARLRVHLAESGRRVNVNDLWIAATAAANGVPIVTQDDDFDPLEGAHGVTVIRV

Download         Length: 405 bp

>T172156 NZ_CP079629:c4099134-4098817 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTTCAGATTGGTTGTGCATGTGGACGTTAAAAAGGAATTGCAGGCGCTTCCGCCCATTGTCCAGGCGAAGATGATCCG
GCAATTAGACAAGTTACGCCAAAATCCCACCGCGCTGAGAGAACCTGACAGTAAACCGCTGGGGCAGGGGCTATTTGAAA
TTCGTGCGTTAGGTTCGGTACAGGGGCGAGGGATCTACGTTTTTCAGCAAGGCAAGACGCTCTTTCTGCTACGGGTTTTT
GTCAAGAAAACGCAAAAAACCCCGTCATCGGAAATTCGCCTGGCGCTGAAGCGATTAGAGGAGATGCGCAATGAGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9462.72 Da        Isoelectric Point: 11.6548

>AT172156 WP_166985934.1 NZ_CP061169:c95502-95242 [Microbacterium sp. HY60]
MAEIAARELRNSTAEVLRRVEAGEPVTITSRGRPVAELTPVRSARRRPISRADLTRRLSRTQADSGLREDLALLAGETTD
DLGPIR

Download         Length: 261 bp

>AT172156 NZ_CP079629:c4098824-4098537 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAGTAAAAAGATCATTGACTGGGATACGTTAAAAACAGAACTGCTTGGCCAGCCTGAGGTTCAGGCTGCATTCGATGC
GCAAGAACGTCAACAGCGATTACGTACTATGCTGGCGCAATGGCGCGAGCAGGCGGGGCTAACCCGAGCCCAGGTGGCGC
AGAGGATGGGGGTGAGTGCGCCAACGGTCTCCAGAATGGAAGCCAATATCACCCGCGCCAGTCTGGATACCTTAACGCGA
TACGCGTTAGCCTGCGGTATAAAGCACCCGCAAGTTTTACTTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References