Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2022338..2022609 Replicon chromosome
Accession NZ_CP061101
Organism Escherichia coli strain 1EC213

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2022468..2022571 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2022338..2022609 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IB009_RS09805 2018893..2019555 - 663 WP_000944256.1 exodeoxyribonuclease X -
IB009_RS09810 2019579..2020235 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
IB009_RS09815 2020337..2020567 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IB009_RS09820 2020706..2021080 + 375 WP_000204699.1 CopC domain-containing protein YobA -
IB009_RS09825 2021084..2021956 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
IB009_RS09830 2021969..2022310 + 342 WP_000976492.1 YebY family protein -
- 2022338..2022609 - 272 - - Antitoxin
- 2022468..2022571 + 104 - - Toxin
IB009_RS09835 2022706..2023362 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
IB009_RS09840 2023363..2023554 - 192 WP_001296140.1 YebW family protein -
IB009_RS09845 2023659..2023895 - 237 WP_001295499.1 DUF1480 family protein -
IB009_RS09850 2024013..2025452 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T172090 NZ_CP061101:2022468-2022571 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT172090 NZ_CP061101:c2022609-2022338 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References