Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 92336..92919 Replicon plasmid p1318-2
Accession NZ_CP061093
Organism Roseomonas marmotae strain 1318

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IAI58_RS18475 Protein ID WP_207448771.1
Coordinates 92632..92919 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IAI58_RS18470 Protein ID WP_207448769.1
Coordinates 92336..92635 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IAI58_RS18450 (IAI58_18440) 87580..88518 + 939 WP_208776182.1 LysR family transcriptional regulator -
IAI58_RS18455 (IAI58_18445) 88769..89047 - 279 WP_237182521.1 hypothetical protein -
IAI58_RS18460 (IAI58_18450) 89138..90847 - 1710 WP_207448765.1 thiamine pyrophosphate-requiring protein -
IAI58_RS18465 (IAI58_18455) 90912..91901 - 990 WP_207448767.1 tripartite tricarboxylate transporter substrate binding protein -
IAI58_RS18470 (IAI58_18460) 92336..92635 + 300 WP_207448769.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
IAI58_RS18475 (IAI58_18465) 92632..92919 + 288 WP_207448771.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IAI58_RS18480 (IAI58_18470) 93140..94129 + 990 WP_207448773.1 UDP-glucose 4-epimerase GalE -
IAI58_RS18485 (IAI58_18475) 94147..94938 + 792 WP_207448775.1 SDR family oxidoreductase -
IAI58_RS18490 (IAI58_18480) 94952..95848 + 897 WP_208776183.1 polysaccharide deacetylase -
IAI58_RS18495 (IAI58_18485) 95858..96325 + 468 WP_207448779.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..102714 102714


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-67)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10641.29 Da        Isoelectric Point: 10.8468

>T172080 WP_207448771.1 NZ_CP061093:92632-92919 [Roseomonas marmotae]
VRLEWSALALADRAAIFDHIAAENPRAAVALDQQLAGRIAALPEFPRRGRPGRVEATRELPLPPTPYIAVYQLRGDTLRI
LRLLHGARLWPDERS

Download         Length: 288 bp

>T172080 NZ_CP061093:92632-92919 [Roseomonas marmotae]
GTGAGGCTGGAATGGTCCGCCCTGGCGCTCGCCGACCGGGCGGCCATCTTCGACCATATCGCGGCGGAGAACCCCCGCGC
GGCCGTGGCGCTGGACCAGCAGCTGGCCGGCCGGATCGCCGCCCTGCCCGAATTTCCGCGGCGCGGGCGCCCGGGACGGG
TGGAGGCAACGCGCGAGCTGCCGCTGCCGCCCACGCCCTATATCGCCGTCTATCAGCTCCGGGGTGATACCCTCCGCATC
CTGCGCCTGCTGCACGGCGCCCGGCTCTGGCCCGATGAACGCTCCTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10883.45 Da        Isoelectric Point: 5.8771

>AT172080 WP_207448769.1 NZ_CP061093:92336-92635 [Roseomonas marmotae]
MPANALIQTRIDPQVKERAGAVLEKMGLTLSDAVRILLTRTANEGALPFALLADPAQHDAWFRAKVREALEDPRPALPQE
EAEALFARRRAEALRGQDG

Download         Length: 300 bp

>AT172080 NZ_CP061093:92336-92635 [Roseomonas marmotae]
ATGCCCGCCAATGCCCTGATCCAGACCCGCATCGACCCACAGGTGAAGGAACGCGCCGGCGCCGTGCTGGAGAAGATGGG
GCTGACCCTGTCGGATGCCGTGCGGATCCTGCTGACCCGCACCGCCAATGAGGGCGCCCTGCCCTTCGCCCTGCTGGCCG
ATCCCGCCCAGCACGATGCCTGGTTCCGCGCCAAGGTGCGCGAGGCTCTGGAAGACCCCCGCCCCGCCCTGCCGCAGGAG
GAGGCCGAGGCTCTCTTCGCGCGCCGCCGGGCGGAGGCGCTGCGCGGGCAGGATGGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References