Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-HipB |
Location | 2103191..2104817 | Replicon | chromosome |
Accession | NZ_CP061083 | ||
Organism | Pantoea sp. MT58 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | E0LV81 |
Locus tag | IAI47_RS09935 | Protein ID | WP_008925194.1 |
Coordinates | 2103492..2104817 (+) | Length | 442 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | E0LV82 |
Locus tag | IAI47_RS09930 | Protein ID | WP_008925195.1 |
Coordinates | 2103191..2103487 (+) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IAI47_RS09915 | 2098666..2100048 | + | 1383 | WP_008925198.1 | M24 family metallopeptidase | - |
IAI47_RS09920 | 2100163..2102208 | + | 2046 | WP_008925197.1 | FUSC family protein | - |
IAI47_RS09925 | 2102548..2102883 | - | 336 | WP_008925196.1 | gamma-glutamylcyclotransferase | - |
IAI47_RS09930 | 2103191..2103487 | + | 297 | WP_008925195.1 | helix-turn-helix domain-containing protein | Antitoxin |
IAI47_RS09935 | 2103492..2104817 | + | 1326 | WP_008925194.1 | type II toxin-antitoxin system HipA family toxin | Toxin |
IAI47_RS09940 | 2105207..2106226 | - | 1020 | WP_008925193.1 | alpha/beta hydrolase | - |
IAI47_RS09945 | 2106717..2107139 | + | 423 | WP_008925192.1 | hydroxyisourate hydrolase | - |
IAI47_RS09950 | 2107156..2107577 | - | 422 | Protein_1936 | hypothetical protein | - |
IAI47_RS09955 | 2107571..2107855 | + | 285 | Protein_1937 | SDR family oxidoreductase | - |
IAI47_RS09960 | 2108100..2109200 | + | 1101 | WP_008925189.1 | NADH:flavin oxidoreductase/NADH oxidase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 442 a.a. Molecular weight: 50159.05 Da Isoelectric Point: 6.0674
>T172070 WP_008925194.1 NZ_CP061083:2103492-2104817 [Pantoea sp. MT58]
MSRRQQRLVIWMNGIQVGFWNKSKGEDTLQYLPEWSADAQGRPLSLSLPFTPGDQIWRGNVVRDYFDNLLPDSEGIRRRL
AMRYQAESLDPFDLLTELGKDCVGAIQLLKEGDEPTDLYCVKYRPLSESEIAMTLRNTTAASLPGRQSDTGDLRLSIAGA
QEKTALLWHDDRWCRPEGNTPTTHIFKLPLGLVGNMKADMSTSVENEWLCSLLLEQFGIPVARTEIAQFEDQKVLVVERF
DRKWSGDQRWIIRLPQEDMCQAAGMSPLRKYQADGGPGISEIMEILSHSDHAEQDRLHFFKAQIIFWVLAATDGHAKNFS
IAIGPQGHYCLTPLYDVLSAWSVIGNGNNQIAWQKCKLAMAARGSSNYYKLYRIQRRHWINHGEQTGLSKKQVEMMMDEI
ISDAPDVIERVRAQLPDQFPSELAERVFDGITQQCRRLAGN
MSRRQQRLVIWMNGIQVGFWNKSKGEDTLQYLPEWSADAQGRPLSLSLPFTPGDQIWRGNVVRDYFDNLLPDSEGIRRRL
AMRYQAESLDPFDLLTELGKDCVGAIQLLKEGDEPTDLYCVKYRPLSESEIAMTLRNTTAASLPGRQSDTGDLRLSIAGA
QEKTALLWHDDRWCRPEGNTPTTHIFKLPLGLVGNMKADMSTSVENEWLCSLLLEQFGIPVARTEIAQFEDQKVLVVERF
DRKWSGDQRWIIRLPQEDMCQAAGMSPLRKYQADGGPGISEIMEILSHSDHAEQDRLHFFKAQIIFWVLAATDGHAKNFS
IAIGPQGHYCLTPLYDVLSAWSVIGNGNNQIAWQKCKLAMAARGSSNYYKLYRIQRRHWINHGEQTGLSKKQVEMMMDEI
ISDAPDVIERVRAQLPDQFPSELAERVFDGITQQCRRLAGN
Download Length: 1326 bp
>T172070 NZ_CP079186:335828-336196 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA
Antitoxin
Download Length: 99 a.a. Molecular weight: 10966.66 Da Isoelectric Point: 10.8315
>AT172070 WP_008925195.1 NZ_CP061083:2103191-2103487 [Pantoea sp. MT58]
MKNVYPIKTLSQLRPLLIGFRKANGLTQKDLSERLGVTQQTYARLEANPARASIERLFKIFTLLGVEMTLSSGISSSAGK
QTEEKGTLENSPARREKW
MKNVYPIKTLSQLRPLLIGFRKANGLTQKDLSERLGVTQQTYARLEANPARASIERLFKIFTLLGVEMTLSSGISSSAGK
QTEEKGTLENSPARREKW
Download Length: 297 bp
>AT172070 NZ_CP079186:335610-335831 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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