172051

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3914518..3915020 Replicon chromosome
Accession NZ_CP061081
Organism Marinomonas arctica strain BSI20414

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IBG28_RS18140 Protein ID WP_111606818.1
Coordinates 3914518..3914772 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IBG28_RS18145 Protein ID WP_111606817.1
Coordinates 3914769..3915020 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IBG28_RS18120 3910065..3910550 + 486 WP_111606822.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
IBG28_RS18125 3910554..3911378 + 825 WP_111606821.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
IBG28_RS18130 3911378..3912229 + 852 WP_111606820.1 pantoate--beta-alanine ligase -
IBG28_RS18135 3912452..3914098 + 1647 WP_111606819.1 glucose-6-phosphate isomerase -
IBG28_RS18140 3914518..3914772 - 255 WP_111606818.1 Txe/YoeB family addiction module toxin Toxin
IBG28_RS18145 3914769..3915020 - 252 WP_111606817.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IBG28_RS18150 3915198..3915938 + 741 WP_111606816.1 hypothetical protein -
IBG28_RS18155 3915952..3917091 - 1140 WP_111606815.1 Fic family protein -
IBG28_RS18160 3917261..3917476 + 216 WP_111606814.1 addiction module protein -
IBG28_RS18165 3918104..3918751 + 648 WP_111606813.1 hypothetical protein -
IBG28_RS18170 3919016..3919624 + 609 WP_111606812.1 YIP1 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10167.66 Da        Isoelectric Point: 9.7406

>T172051 WP_111606818.1 NZ_CP061081:c3914772-3914518 [Marinomonas arctica]
VRLTFSTAAWDQYLYWQSTDKKVLKRINLLIKDIQREPYEGIGKPEPLKHGLAGYWSRRINDEHRIVYKYQDDAILIAQL
RYHY

Download         Length: 255 bp

>T172051 NZ_CP079172:4198166-4198384 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACCTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9175.50 Da        Isoelectric Point: 4.4621

>AT172051 WP_111606817.1 NZ_CP061081:c3915020-3914769 [Marinomonas arctica]
MDAISYTAARANLAKTMAKVCDDHSPVIITRKSESPVVMMSLEDYESMQETTYLLRSPANARVLLESIAELEAGKGVERE
LVE

Download         Length: 252 bp

>AT172051 NZ_CP079172:4197765-4198139 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References