172049

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 3333319..3333890 Replicon chromosome
Accession NZ_CP061081
Organism Marinomonas arctica strain BSI20414

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag IBG28_RS15475 Protein ID WP_111605480.1
Coordinates 3333319..3333630 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag IBG28_RS15480 Protein ID WP_111605481.1
Coordinates 3333630..3333890 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IBG28_RS15455 3329247..3330173 - 927 WP_162623464.1 ABC transporter substrate-binding protein -
IBG28_RS15460 3330428..3331375 - 948 WP_111605477.1 AEC family transporter -
IBG28_RS15465 3331427..3332329 - 903 WP_111605478.1 LysR family transcriptional regulator -
IBG28_RS15470 3332464..3333162 + 699 WP_111605479.1 pirin family protein -
IBG28_RS15475 3333319..3333630 - 312 WP_111605480.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IBG28_RS15480 3333630..3333890 - 261 WP_111605481.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IBG28_RS15485 3334237..3334413 + 177 WP_111605482.1 type II toxin-antitoxin system HicA family toxin -
IBG28_RS15490 3334457..3334870 + 414 WP_111605483.1 type II toxin-antitoxin system HicB family antitoxin -
IBG28_RS15495 3335646..3336596 - 951 WP_111605484.1 hypothetical protein -
IBG28_RS15500 3336639..3337070 - 432 WP_111605485.1 hypothetical protein -
IBG28_RS15505 3337162..3338142 - 981 WP_188322912.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-65)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11837.81 Da        Isoelectric Point: 9.6768

>T172049 WP_111605480.1 NZ_CP061081:c3333630-3333319 [Marinomonas arctica]
MSVTYYLTPDAKSDLVGIHCFTLANWGITQSKQYLFGIRQTIRLLAESPSLGKSRPEIRENVFSFPYGSHVIYYVEGKNQ
VVVFAVLHKSMVPFIHLIERKFI

Download         Length: 312 bp

>T172049 NZ_CP079172:c2774318-2772996 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCGCCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCACCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9333.59 Da        Isoelectric Point: 4.5515

>AT172049 WP_111605481.1 NZ_CP061081:c3333890-3333630 [Marinomonas arctica]
MNTISANEAKTHFGDLLLNAQKSPVQISKNGKPVAVVISVDDYESIEALKLHLLQNKAAQAMKDISKGDLIAGEAFFSEL
EEGLYD

Download         Length: 261 bp

>AT172049 NZ_CP079172:c2774584-2774318 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCACTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References