172048

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 2985235..2985780 Replicon chromosome
Accession NZ_CP061081
Organism Marinomonas arctica strain BSI20414

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag IBG28_RS13810 Protein ID WP_111606949.1
Coordinates 2985484..2985780 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag IBG28_RS13805 Protein ID WP_111606950.1
Coordinates 2985235..2985477 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IBG28_RS13775 2980765..2981763 - 999 WP_111606955.1 branched-chain amino acid aminotransferase -
IBG28_RS13780 2982033..2982914 - 882 WP_111606954.1 diguanylate cyclase -
IBG28_RS13785 2983058..2983390 - 333 WP_111607021.1 DUF1294 domain-containing protein -
IBG28_RS13790 2983535..2984275 + 741 WP_111606953.1 tellurite resistance TerB family protein -
IBG28_RS13795 2984460..2984705 + 246 WP_111606952.1 type II toxin-antitoxin system CcdA family antitoxin -
IBG28_RS13800 2984705..2985022 + 318 WP_111606951.1 CcdB family protein -
IBG28_RS13805 2985235..2985477 + 243 WP_111606950.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IBG28_RS13810 2985484..2985780 + 297 WP_111606949.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IBG28_RS13815 2986102..2986665 - 564 WP_111606948.1 hypothetical protein -
IBG28_RS13820 2986754..2987563 - 810 WP_111606947.1 hypothetical protein -
IBG28_RS13825 2988177..2988500 - 324 WP_111606946.1 hypothetical protein -
IBG28_RS13830 2989594..2990178 - 585 WP_111606944.1 dCTP deaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-63)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11421.13 Da        Isoelectric Point: 10.0230

>T172048 WP_111606949.1 NZ_CP061081:2985484-2985780 [Marinomonas arctica]
MQKTKYKLSKLAQTHLQKIKTYTVHNFSETQWQNYKHTLLTGFQMLADNPAVGRRCDEIYPSGFYFPIGKHTAYFTKEDG
FILIVAVLAQSQRPQNHL

Download         Length: 297 bp

>T172048 NZ_CP079172:2048505-2048607 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8975.15 Da        Isoelectric Point: 4.7914

>AT172048 WP_111606950.1 NZ_CP061081:2985235-2985477 [Marinomonas arctica]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIRDYEELEAMKTDYLKHCFESAKQDLAQGNVVDGEDFLSAL

Download         Length: 243 bp

>AT172048 NZ_CP079172:c2048614-2048469 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References