172047

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2984460..2985022 Replicon chromosome
Accession NZ_CP061081
Organism Marinomonas arctica strain BSI20414

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag IBG28_RS13800 Protein ID WP_111606951.1
Coordinates 2984705..2985022 (+) Length 106 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag IBG28_RS13795 Protein ID WP_111606952.1
Coordinates 2984460..2984705 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IBG28_RS13765 2979656..2979934 - 279 WP_111606957.1 hypothetical protein -
IBG28_RS13770 2980144..2980695 + 552 WP_111606956.1 hypothetical protein -
IBG28_RS13775 2980765..2981763 - 999 WP_111606955.1 branched-chain amino acid aminotransferase -
IBG28_RS13780 2982033..2982914 - 882 WP_111606954.1 diguanylate cyclase -
IBG28_RS13785 2983058..2983390 - 333 WP_111607021.1 DUF1294 domain-containing protein -
IBG28_RS13790 2983535..2984275 + 741 WP_111606953.1 tellurite resistance TerB family protein -
IBG28_RS13795 2984460..2984705 + 246 WP_111606952.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
IBG28_RS13800 2984705..2985022 + 318 WP_111606951.1 CcdB family protein Toxin
IBG28_RS13805 2985235..2985477 + 243 WP_111606950.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
IBG28_RS13810 2985484..2985780 + 297 WP_111606949.1 type II toxin-antitoxin system RelE/ParE family toxin -
IBG28_RS13815 2986102..2986665 - 564 WP_111606948.1 hypothetical protein -
IBG28_RS13820 2986754..2987563 - 810 WP_111606947.1 hypothetical protein -
IBG28_RS13825 2988177..2988500 - 324 WP_111606946.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(3-104)

Antitoxin

Post-segregation antitoxin CcdA

(11-81)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11793.85 Da        Isoelectric Point: 5.0336

>T172047 WP_111606951.1 NZ_CP061081:2984705-2985022 [Marinomonas arctica]
MTQFDVYINPSKSTKQAYPFLLDIQNPILSDLATRIVIPLGKLEYFKKESMQILTPIIEYKDEKLILLTPQIASVPSSIL
KEPIGSLAHLRDDILSALDFAVTGF

Download         Length: 318 bp

>T172047 NZ_CP079172:791209-791619 [Klebsiella pneumoniae subsp. pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATAGCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9116.22 Da        Isoelectric Point: 4.7557

>AT172047 WP_111606952.1 NZ_CP061081:2984460-2984705 [Marinomonas arctica]
MQTLFDSTAPKKAANLSINSDLLAKSRALKINLSAMLENALKEELAKNQAEQWKADNRAAIQSYNEFVEENGCFGDEYRT
F

Download         Length: 246 bp

>AT172047 NZ_CP079172:790962-791228 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References