Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2669457..2669985 Replicon chromosome
Accession NZ_CP061081
Organism Marinomonas arctica strain BSI20414

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IBG28_RS12415 Protein ID WP_111608742.1
Coordinates 2669698..2669985 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IBG28_RS12410 Protein ID WP_111608741.1
Coordinates 2669457..2669708 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IBG28_RS12395 2664943..2667297 - 2355 WP_111608738.1 xanthine dehydrogenase molybdopterin binding subunit -
IBG28_RS12400 2667290..2668786 - 1497 WP_111608739.1 xanthine dehydrogenase small subunit -
IBG28_RS12405 2669043..2669345 + 303 WP_111608740.1 cupin domain-containing protein -
IBG28_RS12410 2669457..2669708 + 252 WP_111608741.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IBG28_RS12415 2669698..2669985 + 288 WP_111608742.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IBG28_RS12420 2670190..2671185 + 996 WP_111608743.1 ABC transporter substrate-binding protein -
IBG28_RS12425 2671208..2671996 + 789 WP_111608783.1 ABC transporter ATP-binding protein -
IBG28_RS12430 2671974..2672765 + 792 WP_111608744.1 ABC transporter permease -
IBG28_RS12435 2672779..2673255 + 477 WP_111608745.1 nucleoside deaminase -
IBG28_RS12440 2673362..2674348 + 987 WP_111608746.1 isopenicillin N synthase family oxygenase -
IBG28_RS12445 2674432..2674953 - 522 WP_111608747.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11045.02 Da        Isoelectric Point: 10.6166

>T172045 WP_111608742.1 NZ_CP061081:2669698-2669985 [Marinomonas arctica]
MTYKLKFLPAALKEWRKLAPNIQTQFKKKLAERLDNPHVPASKLRGYDSVYKIKLRTSGYRLAYEVIDDEVVVYVLAIGK
RNKDTVYKKLASRVS

Download         Length: 288 bp

>T172045 NZ_CP079165:58923-59405 [Klebsiella pneumoniae subsp. pneumoniae]
GTGGGACGTATAACCACGCCCGAGCCGTTATCCAGCTCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGACGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGTAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGCGCCGATTT
ACTCCACGATGCAGTTCTACGGTGTTATCGCGTAGCTGAGAACATTGGGGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9071.43 Da        Isoelectric Point: 4.4000

>AT172045 WP_111608741.1 NZ_CP061081:2669457-2669708 [Marinomonas arctica]
MRQVLANYTASISELKKNPTALLNESGGSAIAILNHNKPAAYLVPAEAYELLMEMVDDIELAKLVEARRTDLSKAIEVSL
DDL

Download         Length: 252 bp

>AT172045 NZ_CP079165:58669-58935 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCTGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTGGAGATGGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References