Detailed information of TA system TA172041

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 777361..777883
• Replicon: chromosome
• Accession: NZ_CP061081
• Organism: Marinomonas arctica strain BSI20414

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IBG28_RS03600
• Protein ID: WP_111607190.1
• Coordinates: 777599..777883 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: IBG28_RS03595
• Protein ID: WP_111607037.1
• Coordinates: 777361..777609 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IBG28_RS03575	772786..773973	+	1188	WP_111607041.1	MFS transporter	-
IBG28_RS03580	773993..774808	+	816	WP_111607040.1	2,5-didehydrogluconate reductase DkgB	-
IBG28_RS03585	775326..776375	+	1050	WP_111607039.1	Stealth CR1 domain-containing protein	-
IBG28_RS03590	776447..777178	-	732	WP_188322953.1	acid phosphatase AphA	-
IBG28_RS03595	777361..777609	+	249	WP_111607037.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
IBG28_RS03600	777599..777883	+	285	WP_111607190.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IBG28_RS03605	777903..778265	-	363	WP_111607036.1	hypothetical protein	-
IBG28_RS03610	778376..780481	-	2106	WP_188322954.1	hypothetical protein	-
IBG28_RS03615	780635..782086	-	1452	WP_111607034.1	molybdate ABC transporter ATP-binding protein ModF	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (12-74)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11014.96 Da
• Isoelectric Point: 10.6699

>T172041 WP_111607190.1 NZ_CP061081:777599-777883 [Marinomonas arctica]
MTYKLEFKKSALKEWRKLGATLQQQFKKKLIERLDHPHVPASKLSGADNLYKIKLRQSGYRLVYEVQDDVVIVTVLAVGK
RERNEVYKNAIKRV

Nucleotide

• Length: 285 bp

>T172041 NZ_CP079164:2774118-2774651 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8886.19 Da
• Isoelectric Point: 4.4143

>AT172041 WP_111607037.1 NZ_CP061081:777361-777609 [Marinomonas arctica]
MTSRILSDVAASITEFKANPMKVAASAHGKAVAVLNRNEPAFYCVPAEAYEALMDKLEDMELISLAKERVNEESISVSIA
DL

Nucleotide

• Length: 249 bp

>AT172041 NZ_CP079164:2773841-2774107 [Klebsiella pneumoniae subsp. pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA