Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 5282538..5283229 Replicon chromosome
Accession NZ_CP061080
Organism Mesirhizobium sp. NIBR3 strain N3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IAI54_RS24920 Protein ID WP_187969745.1
Coordinates 5282804..5283229 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IAI54_RS24915 Protein ID WP_187969744.1
Coordinates 5282538..5282807 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IAI54_RS24890 5278237..5279307 - 1071 WP_187969739.1 heat-inducible transcriptional repressor HrcA -
IAI54_RS24895 5279440..5280156 + 717 WP_187969740.1 ribonuclease PH -
IAI54_RS24900 5280193..5280606 + 414 WP_187969741.1 VOC family protein -
IAI54_RS24905 5280603..5281250 + 648 WP_187969742.1 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase -
IAI54_RS24910 5281247..5282449 + 1203 WP_187969743.1 coproporphyrinogen III oxidase -
IAI54_RS24915 5282538..5282807 + 270 WP_187969744.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IAI54_RS24920 5282804..5283229 + 426 WP_187969745.1 type II toxin-antitoxin system VapC family toxin Toxin
IAI54_RS24925 5283226..5284131 + 906 WP_187969746.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
IAI54_RS24930 5284121..5284498 + 378 WP_187969747.1 YraN family protein -
IAI54_RS24935 5284572..5285405 + 834 WP_187969748.1 cyclase family protein -
IAI54_RS24940 5285488..5287098 + 1611 WP_187969749.1 GMC family oxidoreductase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15755.04 Da        Isoelectric Point: 5.2655

>T172036 WP_187969745.1 NZ_CP061080:5282804-5283229 [Mesirhizobium sp. NIBR3]
MNYLLDTNVLSESSRPQPSPDVMRWLAELDEDRGFVSVITVAELRRGALILAPGRRRDSLMSWIDGELRDRFAGRIIPVD
AEVADRWSDIMVARRSEGRGLGVMDGFLAATALVRGLTVVTRNIRDFAFLGDRVVNPWGTP

Download         Length: 426 bp

>T172036 NZ_CP079164:c1285604-1285194 [Klebsiella pneumoniae subsp. pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGAAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9979.35 Da        Isoelectric Point: 5.1832

>AT172036 WP_187969744.1 NZ_CP061080:5282538-5282807 [Mesirhizobium sp. NIBR3]
VSKSANKDLDVWTLANAKARLSEVVDRAQDVPQMVTRNGRPAVVIVSAEEWKRKTDRKGNLAEFLLASPLRGLDLDVERV
DEPPRELDL

Download         Length: 270 bp

>AT172036 NZ_CP079164:c1285851-1285585 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References